{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T13:35:49Z","timestamp":1775655349170,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T00:00:00Z","timestamp":1471996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the incidence of twin\u2010twin transfusion syndrome (TTTS) and the perinatal outcome at 28 days of age in monochorionic diamniotic (MCDA) pregnancies complicated with isolated polyhydramnios (I\u2010Poly) and isolated oligohydramnios (I\u2010Oligo) diagnosed &lt; 26 weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective study of women with MCDA pregnancies diagnosed with I\u2010Poly or I\u2010Oligo before 26 weeks of gestation over a period of six years. The incidence of subsequent TTTS and neonatal outcome in terms of intact survival (IS) at 28 days of age were evaluated. Intact survival was defined as being alive without any neurological complications at 28 days of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 30 cases of I\u2010Poly and 53 of I\u2010Oligo that were eligible as per the inclusion criteria. Subsequent TTTS were complicated in six (20.0%) of the I\u2010Poly and 26 (49.0%) of the I\u2010Oligo cases. Among subjects with I\u2010Poly, 17 had spontaneously normalized amniotic fluid volume. Prolonged oligohydramnios until intrauterine death, delivery or the onset of emerging TTTS was noted in 16 cases of I\u2010Oligo. Both the twins exhibited IS in 26 (86.7%) cases of I\u2010Poly and 31 (58.4%) cases of I\u2010Oligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>One\u2010fifth of I\u2010Poly and half of I\u2010Oligo MCDA twins at &lt; 26 weeks of gestation potentially develop TTTS. I\u2010Oligo in particular should be regarded as a high\u2010risk condition as neonatal IS is less than 60%.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13106","type":"journal-article","created":{"date-parts":[[2016,8,25]],"date-time":"2016-08-25T04:23:20Z","timestamp":1472099000000},"page":"1657-1665","source":"Crossref","is-referenced-by-count":4,"title":["Perinatal outcome of monochorionic diamniotic twin pregnancies complicated with isolated amniotic fluid volume abnormality of one twin less than 26 weeks of gestation"],"prefix":"10.1111","volume":"42","author":[{"given":"Hiroshi","family":"Kawamura","sequence":"first","affiliation":[{"name":"Department of Maternal Fetal Medicine Osaka Medical Center and Research Institute for Maternal and Child Health  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine Osaka Medical Center and Research Institute 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