{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:23:34Z","timestamp":1790727814530,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T00:00:00Z","timestamp":1474243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to examine the association between CD4 count, human papilloma virus (HPV) infection, and the risk of cervical intraepithelial neoplasia among HIV\u2010infected women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted among 104 HIV\u2010infected women attending an antiretroviral therapy clinic. They underwent Pap smear and cervical HPV DNA testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall prevalence of HPV infection was 57.7%. HPV 16 was the commonest genotype found (38.5%); HPV 16 and 18 put together contributed to 73.3% of HPV infection; 27.5% of HIV\u2010infected women had squamous cell abnormalities. Cervical intraepithelial neoplasia was less likely among women with CD4 count\u00a0&gt;\u00a0500\/mm<jats:sup>3<\/jats:sup> (12%) and in those without opportunistic infections (17.8%). The prevalence of high\u2010risk HPV infection was higher in women with high\u2010grade squamous intraepithelial lesions or greater lesions (85.7%) as compared to women with normal cytology (52.1%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The high prevalence of HPV infection and cervical intraepithelial neoplasia in HIV\u2010infected women warrants the need for regular Pap smear screening in these women and routine HPV vaccination for adolescents to reduce the burden of cervical cancer in India.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13111","type":"journal-article","created":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T12:17:07Z","timestamp":1474287427000},"page":"1822-1828","source":"Crossref","is-referenced-by-count":10,"title":["Cervical cytological abnormalities and human papilloma virus infection in women infected with HIV in Southern India"],"prefix":"10.1111","volume":"42","author":[{"given":"Suchitra","family":"Thunga","sequence":"first","affiliation":[{"name":"Department of OBG, Kasturba Medical College Manipal University  Mangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusmitha","family":"Andrews","sequence":"additional","affiliation":[{"name":"Life Line Hospital  Pathanamthitta Kerala India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Ramapuram","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kasturba Medical College Manipal University  Mangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kapaettu","family":"Satyamoorthy","sequence":"additional","affiliation":[{"name":"Centre for Molecular and Cellular Biology, School of Life Sciences Manipal University  Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hema","family":"Kini","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College Manipal University  Mangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Unnikrishnan","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Kasturba Medical College Manipal University  Mangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabha","family":"Adhikari","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kasturba Medical College Manipal University  Mangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakhar","family":"Singh","sequence":"additional","affiliation":[{"name":"Kasturba Medical College Manipal University  Mangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shama Prasada","family":"Kabekkodu","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, School of Life Sciences Manipal University  Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samatha","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, School of Life Sciences Manipal University  Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anagha","family":"Kadam","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, School of Life Sciences Manipal University  Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash K","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Wake Forest School of Medicine  Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,19]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"BruniL Barrionuevo\u2010 RosarL SerranoBet al.ICO Information Centre on HPV and Cancer (HPV information center). 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