{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:17:38Z","timestamp":1784740658993,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,10,8]],"date-time":"2016-10-08T00:00:00Z","timestamp":1475884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>With the availability of the highly sensitive \u03b2\u2010human chorionic gonadotropin (\u03b2\u2010hCG) assays, all pregnancies, including ectopic pregnancies (EP), are expected to have detectable serum \u03b2\u2010hCG at 4 weeks\u2019 gestation or 9 days following blastocyst transfer. To our knowledge, this is the first report of a woman who underwent <jats:italic>in vitro<\/jats:italic> fertilization, had undetectable serum \u03b2\u2010hCG 9 days after blastocyst transfer, and was then diagnosed with a ruptured abdominal EP and intra\u2010abdominal bleeding 19 days later. This case highlights that the rise in serum \u03b2\u2010hCG might be delayed in abdominal EP compared to intrauterine pregnancy. This delay should raise the suspicion for EP, thus meriting close monitoring. Moreover, in the absence of menstruation, an undetectable serum \u03b2\u2010hCG 9 days post\u2010blastocyst transfer should prompt \u03b2\u2010hCG measurement in 2\u20133 days to avoid the misdiagnosis of an EP.<\/jats:p>","DOI":"10.1111\/jog.13127","type":"journal-article","created":{"date-parts":[[2016,10,13]],"date-time":"2016-10-13T06:58:49Z","timestamp":1476341929000},"page":"1886-1888","source":"Crossref","is-referenced-by-count":8,"title":["Abdominal ectopic pregnancy with undetectable serum \u03b2\u2010human chorionic gonadotropin 9 days following blastocyst transfer"],"prefix":"10.1111","volume":"42","author":[{"given":"Mohamad","family":"Irani","sequence":"first","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine Weill Cornell Medicine  New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rony T.","family":"Elias","sequence":"additional","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine Weill Cornell Medicine  New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Pereira","sequence":"additional","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine Weill Cornell Medicine  New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Gunnala","sequence":"additional","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine Weill Cornell Medicine  New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zev","family":"Rosenwaks","sequence":"additional","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine Weill Cornell Medicine  New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.184.5.01841600"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a136315"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.2.383"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0810384"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000198635.25135.e7"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13127","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13127","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:18:11Z","timestamp":1695500291000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,8]]},"references-count":5,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/jog.13127"],"URL":"https:\/\/doi.org\/10.1111\/jog.13127","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,8]]}}}