{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T21:56:41Z","timestamp":1764194201061},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T00:00:00Z","timestamp":1481241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Noise exposure during pregnancy has been reported to cause fetal hearing impairment. However, little is known about the effects of noise exposure during various gestational stages on postnatal hearing. In the present study, we investigated the effects of noise exposure on auditory brainstem response (ABR) at the early, mid\u2010, and late gestational periods in newborn guinea pigs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pregnant guinea pigs were exposed to 4\u2010kHz pure tone at a 120\u2010dB sound pressure level for 4 h. We divided the animals into four groups as follows: the control, early gestational exposure, mid\u2010gestational exposure, and late gestational exposure groups. ABR thresholds and latencies in newborns were recorded using 1\u2010, 2\u2010, and 4\u2010kHz tone burst on postnatal days 1, 7, 14, and 28. Changes in ABR thresholds and latencies were measured between the 4 \u00d7 4 and 4 \u00d7 3 factorial groups mentioned above (gestational periods \u00d7 postnatal days, gestational periods \u00d7 frequencies).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The thresholds were low in the order of control group\u00a0&lt;\u00a0early gestational exposure group\u00a0&lt;\u00a0mid\u2010gestational exposure group and late gestational exposure group. Noise exposure during pregnancy influenced ABR thresholds in neonatal guinea pigs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first study to show that noise exposure during the early, mid\u2010, and late gestational periods significantly elevated ABR thresholds in neonatal guinea pigs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13194","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T14:06:20Z","timestamp":1481292380000},"page":"78-86","source":"Crossref","is-referenced-by-count":1,"title":["Effects of noise exposure on neonatal auditory brainstem response thresholds in pregnant guinea pigs at different gestational periods"],"prefix":"10.1111","volume":"43","author":[{"given":"Chihiro","family":"Morimoto","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Nara Medical University  Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Nario","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Nara Prefecture General Medical Center  Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Nara Medical University  Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Shimokura","sequence":"additional","affiliation":[{"name":"Interdisciplinary Graduate School of Science &amp; Engineering, Area of Architecture and Production Design Engineering Shimane University  Matsue Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hosoi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Nara Medical University  Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Kitahara","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Nara Medical University  Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700100410"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dev.420150202"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(94)90190-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-199902000-00003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00188388"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487309121476"},{"key":"e_1_2_7_8_1","first-page":"1","article-title":"Functional and anatomical aspects in the development of the cochlea of maturing guinea pigs","volume":"76","author":"Ohmura M","year":"1973","journal-title":"Pract Otolaryngol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197403000-00008"},{"key":"e_1_2_7_10_1","first-page":"337","article-title":"Effects of noise coming from textile weaving shops on the auditory organ of guinea pig fetuses","volume":"30","author":"Daniel T","year":"1976","journal-title":"Otolaryngol Pol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(79)90016-8"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90866-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aud.0000191942.36672.f3"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-199004000-00003"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/253044a0"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13194","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T13:13:24Z","timestamp":1696252404000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,9]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/jog.13194"],"URL":"https:\/\/doi.org\/10.1111\/jog.13194","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,9]]}}}