{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:11:54Z","timestamp":1791490314967,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,17]],"date-time":"2016-12-17T00:00:00Z","timestamp":1481932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Beh\u00e7et's disease (BD) is a rare and multisystemic vasculitis disease. In this study, we investigated whether BD had any effect on the biochemical components of first and second trimester aneuploidy screening tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case\u2013control retrospective study was conducted with 32 pregnant women with BD and 60 healthy pregnant women as controls. All pregnant womens\u2019 first trimester maternal serum pregnancy\u2010associated plasma protein\u2010A, free <jats:italic>\u03b2<\/jats:italic>\u2010human chorionic gonadotropin and second trimester serum alpha\u2010fetoprotein, unconjugated estriol and total human chorionic gonadotropin levels were examined from medical records. First and second serum screening markers were compared between pregnancies with BD and without.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no difference in age, body mass index and obstetric history between the groups. No significant difference was observed between the groups in terms of first and second trimester serum screening test results in the absence of aneuploidy or neural tube defect. Gestational age at birth, birth weight and neonatal intensive care admission rate were also similar between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both first and second serum screening tests for Down syndrome may be recommended to pregnant women with BD without the need to readjust these markers. Pregnancy with BD was not associated with adverse perinatal outcome with respect to gestational age at birth or birth weight.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13237","type":"journal-article","created":{"date-parts":[[2016,12,17]],"date-time":"2016-12-17T17:41:53Z","timestamp":1481996513000},"page":"511-515","source":"Crossref","is-referenced-by-count":9,"title":["Influence of Beh\u00e7et's disease on first and second trimester serum screening markers"],"prefix":"10.1111","volume":"43","author":[{"given":"Zehra Vural","family":"Y\u0131lmaz","sequence":"first","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclenay Gen\u00e7osmano\u011flu","family":"T\u00fcrkmen","sequence":"additional","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elif","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Dr. Sami Ulus Women's and Children's Health Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Korkut","family":"Da\u011flar","sequence":"additional","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"K\u0131rba\u015f","sequence":"additional","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Sanhal","sequence":"additional","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aykan","family":"Y\u00fccel","sequence":"additional","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Uygur","sequence":"additional","affiliation":[{"name":"Department of Perinatology Zekai Tahir Burak Women's Health Education and Training Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910213411707"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20308"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ker449"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-199401000-00007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.308"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6653.883"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1737"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200102)21:2<143::AID-PD998>3.0.CO;2-B"},{"key":"e_1_2_6_10_1","first-page":"1820","article-title":"First and second trimester biochemical markers in familial mediterranean fever","volume":"17","author":"Turkcapar F","year":"2013","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_6_11_1","first-page":"1078","article-title":"Criteria for diagnosis of Beh\u00e7et's disease","volume":"335","author":"International Study Group for Beh\u00e7et's Disease","year":"1990","journal-title":"Lancet"},{"key":"e_1_2_6_12_1","first-page":"863","article-title":"Committee opinion no 611: Method for estimating due date","volume":"124","year":"2014","journal-title":"ObstetGynecol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200701000-00054"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb11618.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5165"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)32973-5"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31814b23da"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2008.04.021"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2010.04.003"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00761.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38052"},{"key":"e_1_2_6_22_1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.12891\/ceog16762014","article-title":"Behcet disease and pregnancy","volume":"41","author":"Gungor AN","year":"2014","journal-title":"Clin Exp Obstet Gynecol"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12386"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:28:39Z","timestamp":1696249719000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,17]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/jog.13237"],"URL":"https:\/\/doi.org\/10.1111\/jog.13237","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,17]]}}}