{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:56:39Z","timestamp":1790470599934,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to assay the clinical characteristics of persistent ectopic pregnancy (PEP) and its influence on ongoing pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed 2498 patients who received salpingostomies as primary management for ectopic pregnancies from January 2004 to December 2009, using medical records and telephone inquiries. Clinical characteristics of the 52 patients (2.08%) who were diagnosed with PEP after salpingostomy were compared with those who received satisfactory treatment. The odds ratios and 95% confidential intervals were calculated for each variable by univariate and (for significantly different factors) multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Preoperatively, patients with PEP after salpingostomy significantly differed from the non\u2010PEP patients in gestational age, mass size and pelvic adhesiolysis. Serum \u03b2\u2010human chorionic gonadotropin levels in PEP patients were monitored after surgery, which had declined by 28.31% on postoperative day (POD) 4, 40.22% on POD 7, 51.46% on POD 10 and 53.43% on POD 21. Repeat ectopic pregnancy (REP) tended to occur more frequently in PEP patients (PEP: 5 cases, 10.20%; non\u2010PEP: 4 cases, 2.80%; <jats:italic>P<\/jats:italic> = 0.034). Multivariate analysis showed that pelvic adhesions and PEP were the strongest independent predictors of REP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gestational age, mass size and pelvic adhesions were significantly correlated with PEP. PEP was an independent prognostic factor for REP. However, a multicenter study is needed to support and extend our findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13251","type":"journal-article","created":{"date-parts":[[2017,1,27]],"date-time":"2017-01-27T04:57:50Z","timestamp":1485493070000},"page":"564-570","source":"Crossref","is-referenced-by-count":15,"title":["Clinical characteristics of persistent ectopic pregnancy after salpingostomy and influence on ongoing pregnancy"],"prefix":"10.1111","volume":"43","author":[{"given":"Yongli","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiqiang","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoping","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,26]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","article-title":"Pregnancy\u2010related mortality surveillance\u2013United States, 1991\u20131999","volume":"52","author":"Chang J","year":"2003","journal-title":"MMWR Surveill Summ"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0810384"},{"key":"e_1_2_6_4_1","first-page":"378","article-title":"Comparison of persistent ectopic pregnancy after laparoscopic salpingostomy versus salpingostomy at laparotomy for ectopic pregnancy","volume":"81","author":"Seifer DB","year":"1993","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200008000-00004"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2010.06.034"},{"key":"e_1_2_6_7_1","first-page":"803","article-title":"Fertility after ectopic pregnancy. 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