{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T02:32:36Z","timestamp":1695263556493},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T00:00:00Z","timestamp":1485993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This quality Improvement study evaluated the applicability of our protocol for early\u2010onset severe pre\u2010eclampsia, prepared in April 2013.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected data from all women with early\u2010onset severe pre\u2010eclampsia treated at our hospital between March 2008 and August 2015. Neonatal and maternal outcomes were compared between protocol\u2010based (<jats:italic>n<\/jats:italic> = 17) and non\u2010protocol\u2010based management groups (<jats:italic>n<\/jats:italic> = 28).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The latency period was significantly longer in the protocol\u2010based than in the non\u2010protocol\u2010based group (21.9 \u00b1 3.7 vs 11.0 \u00b1 2.9 days). Gestational age at delivery was significantly more advanced in the protocol\u2010based than in the non\u2010protocol\u2010based group (31.4 \u00b1 0.6 vs 29.8 \u00b1 0.4 weeks). Serious neonatal complications were significantly less prevalent in the protocol\u2010based than in the non\u2010protocol\u2010based group (26% vs 79%). Among the protocol components, magnesium sulfate use was the only independent factor contributing to the absence of serious neonatal complications. The percentages of women exhibiting persistent proteinuria or hypertension at one, two and three months post\u2010partum were similar between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Strict adherence to our protocol improved neonatal outcomes without affecting maternal prognosis. Routine use of magnesium sulfate could be the most important component of the protocol.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13265","type":"journal-article","created":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T09:33:56Z","timestamp":1486028036000},"page":"644-652","source":"Crossref","is-referenced-by-count":3,"title":["Introduction of management protocol for early\u2010onset severe pre\u2010eclampsia"],"prefix":"10.1111","volume":"43","author":[{"given":"Chieko","family":"Sakae","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiyasu","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Kanbayashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuko","family":"Taga","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuko","family":"Emoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Mise","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Otsu Red Cross Hospital  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,2]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1070","article-title":"Aggressive or expectant management for patients with severe preeclampsia between 28 and 34 weeks' gestation: A randomized controlled trial","volume":"76","author":"Odendaal HJ","year":"1990","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(94)90104-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641950802601252"},{"key":"e_1_2_7_5_1","first-page":"CD003106","article-title":"Interventionist versus expectant care for severe pre\u2010eclampsia between 24 and 34 weeks' gestation","volume":"7","author":"Churchill D","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_6_1","first-page":"CD004454","article-title":"Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth","author":"Roberts D","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1097\/01.AOG.0000433994.46087.85","article-title":"Committee Opinion No. 573: Magnesium sulfate use in obstetrics","volume":"122","author":"American College of Obstetricians and Gynecologists Committee on Obstetric Practice Society for Maternal\u2010Fetal Medicine","year":"2013","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_8_1","first-page":"CD001060","article-title":"Magnesium sulphate for preventing preterm birth in threatened preterm labour","volume":"8","author":"Crowther CA","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.07.017"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70047-9"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.9008"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000263589"},{"key":"e_1_2_7_13_1","first-page":"159","article-title":"ACOG Practice Bulletin. 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