{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:50:36Z","timestamp":1767991836077,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,2,11]],"date-time":"2017-02-11T00:00:00Z","timestamp":1486771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Our aim was to examine the potential roles of ischemia modified albumin(IMA) and D\u2010dimer as reliable early diagnostic markers of ovarian torsion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>24 Wistar albino rats were included and randomized into three groups. Control (sham) rats underwent laparotomy then bilateral ovaries removed for histopathological examination and concomitant blood sampling for IMA and D\u2010dimer assays after 4 h. In the remaining groups, ovarian ischemia was achieved by rotating bilateral ovaries 1080\u00b0 clockwise then blood samples were obtained and ovaries were removed after 4\u00a0h and 24 h. IMA and D\u2010dimer levels as well as the histopathological injury scores were assessed in all groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A statistically higher significant difference in D\u2010dimer levels in the 4\u2010h torsion group (Group 2) than the other groups (<jats:italic>P<\/jats:italic> = 0.001, <jats:italic>P<\/jats:italic> &lt; 0.01).<\/jats:p><jats:p>Despite absence of statistical significance, the difference in IMA levels between the groups was close to statistical significance (<jats:italic>P<\/jats:italic> = 0.064; <jats:italic>P<\/jats:italic> &gt; 0.05); accordingly IMA levels were higher in the 24\u2010h torsion group (Group 3), than in 4\u2010h torsion (Group 2) or sham (Group 1) group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclus\u0131on<\/jats:title><jats:p>Our results suggest that D\u2010dimer may represent a valuable acute marker of ovarian torsion. The cut\u2010off value for D\u2010dimer was 402 ng\/ml. Although rats in Group3 had higher IMA than in other groups, the difference was only close to statistical significance. Also, increasing duration of torsion was associated with reduced D\u2010dimer levels, while IMA levels exhibited an increase during the 24 h period. In contrast with previous studies, IMA appeared to be a potential marker in the long term rather than the short term.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13281","type":"journal-article","created":{"date-parts":[[2017,2,11]],"date-time":"2017-02-11T13:46:41Z","timestamp":1486820801000},"page":"895-901","source":"Crossref","is-referenced-by-count":6,"title":["The Role of Ischemia Modified Albumin and D\u2010dimer as Early or Late Biochemical Markers in Ovarian Torsion"],"prefix":"10.1111","volume":"43","author":[{"given":"Ayca","family":"Karatas Gurgun","sequence":"first","affiliation":[{"name":"Bafra State Hospital Gynecology and Obstetric"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Is\u0131k","family":"Kaban","sequence":"additional","affiliation":[{"name":"\u0130stanbul Training and Research Hospital Gynecology and Obstetric"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nurettin","family":"Aka","sequence":"additional","affiliation":[{"name":"Haydarpasa Numune Training And Research Hospital Gynecology and Obstetric"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Mentese","sequence":"additional","affiliation":[{"name":"Karadeniz Technical University Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fugen","family":"Aker","sequence":"additional","affiliation":[{"name":"Haydarpasa Numune Training and Research Hospital Patology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet R\u0131za","family":"Uras","sequence":"additional","affiliation":[{"name":"Haydarpasa Numune Training and Research Hospital Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-009-2396-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.2001.01846.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000097644"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(00)00255-9"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2009.06.007"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4645"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deq378"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0730261"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjem.2016.02.004"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.12.022"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2010.01.006"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deq378"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.03.073"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000367787"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2010.02.006"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13281","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T15:35:16Z","timestamp":1696174516000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,11]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/jog.13281"],"URL":"https:\/\/doi.org\/10.1111\/jog.13281","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,11]]}}}