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AFE is a rare condition but one of the most serious obstetrical complications, resulting in a high mortality rate among pregnant women. Despite earlier recognition and intensive critical management, we often encounter patients who unfortunately do not recover from the exacerbation of AFE\u2010related conditions. A major concern is that there are no effective evidence\u2010based therapies for AFE, because its pathophysiology is still not well understood. This article reviewed AFE, focusing on the pathology and currently proposed pathophysiology.<\/jats:p>","DOI":"10.1111\/jog.13284","type":"journal-article","created":{"date-parts":[[2017,2,11]],"date-time":"2017-02-11T08:12:40Z","timestamp":1486800760000},"page":"627-632","source":"Crossref","is-referenced-by-count":63,"title":["Amniotic fluid embolism: Pathophysiology from the perspective of pathology"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1461-5618","authenticated-orcid":false,"given":"Naoaki","family":"Tamura","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynaecology Hamamatsu University School of Medicine  Hamamatsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6216-0729","authenticated-orcid":false,"given":"Mustari","family":"Farhana","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynaecology Hamamatsu University School 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