{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T06:22:54Z","timestamp":1775283774235,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T00:00:00Z","timestamp":1499990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aimed to determine the frequency of endometrial cancer in infertile women undergoing hysteroscopic endometrial polypectomy for endometrial polyps.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 1035 infertile patients who underwent office\u2010based hysteroscopic polypectomy at Sugiyama Clinic Marunouchi between July 2011 and October 2015 were eligible for this retrospective study. All patients had been diagnosed with endometrial polyps via hysterofiberscopy prior to operation, and they underwent hysteroscopic endometrial polypectomy using a resectoscope with monopolar resection. Surgical specimens were examined histopathologically. Characteristics of patients diagnosed with endometrial cancer on histopathological examination were evaluated retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of patients was 32\u00a0years (range, 19\u201344\u00a0years). On histopathological examination, endometrial cancer was found in 10 patients (0.97%). Each histological type of endometrial cancer was represented as follows: three cases of endometrioid adenocarcinoma G1; one of endometrioid adenocarcinoma G2; two of endometrioid adenocarcinoma G3; and four of atypical endometrial hyperplasia. The median age of endometrial cancer patients was 34\u00a0years (range, 28\u201341\u00a0years), and the median body mass index was 21.2\u00a0kg\/m<jats:sup>2<\/jats:sup> (range, 16.7\u201329.9\u00a0kg\/m<jats:sup>2<\/jats:sup>). Nine endometrial cancer patients were nulliparous, and all had undergone infertility treatment, with only one woman having delivered a healthy baby. An ovulation disorder was noted in four patients, with obesity (body mass index\u00a0&gt;\u00a025\u00a0kg\/m<jats:sup>2<\/jats:sup>) in just two. Polycystic ovary syndrome was concomitantly observed in one patient. However, abnormal vaginal bleeding was not noted in any of these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hysteroscopic polypectomy should be performed when endometrial polyps are detected on investigational screening, and surgical specimens should be checked for the presence of malignancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13408","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T12:36:50Z","timestamp":1500035810000},"page":"1465-1471","source":"Crossref","is-referenced-by-count":14,"title":["Frequency of endometrial cancer and atypical hyperplasia in infertile women undergoing hysteroscopic polypectomy"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0317-5386","authenticated-orcid":false,"given":"Yasushi","family":"Kuribayashi","sequence":"first","affiliation":[{"name":"Reproductive Medicine and Surgery Sugiyama Clinic Marunouchi  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Division of Reproductive Medicine Sugiyama Clinic  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Reproductive Medicine and Surgery Sugiyama Clinic Marunouchi  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Motoyama","sequence":"additional","affiliation":[{"name":"Reproductive Medicine and Surgery Sugiyama Clinic Marunouchi  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rikikazu","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Division of Reproductive Medicine Sugiyama Clinic  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318162f690"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000255980.88205.15"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2012.23.2.120"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(91)90246-2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000164812.02181.d5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.00997.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/107327480901600103"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2011.09.003"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(88)90011-7"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.02.015"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)01792-1"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2015.06.004"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850715)56:2<403::AID-CNCR2820560233>3.0.CO;2-X"},{"key":"e_1_2_7_15_1","first-page":"417","article-title":"Adenocarcinoma of the endometrium in women 40 years of age or younger","volume":"64","author":"Gallup DG","year":"1984","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2004.02.002"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000080189"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079004317.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.09.876"},{"key":"e_1_2_7_20_1","first-page":"117","article-title":"The risk of premalignant and malignant pathology in endometrial polyps: Should every polyp be resected?","volume":"59","author":"Papadia A","year":"2007","journal-title":"Minerva Ginecol"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/91.19.1654"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d3954"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-992926"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2013.04.004"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.06.003"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmu060"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60269-X"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1200\/EdBook_AM.2013.33.e222"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.01.058"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn318"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwi084"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyd081"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyl084"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep002"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.01.003"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.11.028"},{"key":"e_1_2_7_37_1","first-page":"3047","article-title":"Fertility\u2010sparing management of grade 2 and 3 endometrial adenocarcinomas","volume":"31","author":"Koskas M","year":"2011","journal-title":"Anticancer Res"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T14:44:38Z","timestamp":1695566678000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,14]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1111\/jog.13408"],"URL":"https:\/\/doi.org\/10.1111\/jog.13408","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,14]]}}}