{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T08:02:22Z","timestamp":1774425742036,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T00:00:00Z","timestamp":1509580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aimed to assess the accuracy and effectiveness of fetal cardiac screening for congenital heart disease (<jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>) during the second trimester by general obstetricians in a non\u2010selected population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this multicenter, prospective cohort study of fetal cardiac screening, four\u2010chamber and three\u2010vessel views were recorded by obstetricians at 18\u201321\u2009gestational weeks (GW). A total of 3005 fetuses that were scheduled for delivery at our institution were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010seven newborns were born with <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> (1.2%). On excluding 23 cases of ventricular septal defects, the prenatal detection rate of <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> was 42.8%. Although six cases (75.0%) of severe structural abnormality were diagnosed prenatally, the prenatal detection rate of valvular abnormalities was 0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>One\u2010point ultrasound screening of the fetal heart using a combination of four\u2010chamber and three\u2010vessel views at 18\u201321\u2009GW by general obstetricians in a non\u2010selected population may be useful for detecting severe structural abnormalities but not valvular abnormalities. However, this limitation may be improved by conducting another fetal cardiac screening at approximately 30\u2009GW along with the routine use of color <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>oppler.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13472","type":"journal-article","created":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T08:36:46Z","timestamp":1509611806000},"page":"49-53","source":"Crossref","is-referenced-by-count":16,"title":["Effectiveness of fetal cardiac screening for congenital heart disease using a combination of the four\u2010chamber view and three\u2010vessel view during the second trimester scan"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6656-1909","authenticated-orcid":false,"given":"Mina","family":"Itsukaichi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Niigata University Graduate School of Medical and Dental Sciences  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehiro","family":"Serikawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Niigata University Graduate School of Medical and Dental Sciences  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Yoshihara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Niigata University Graduate School of Medical and Dental Sciences  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Niigata University School of Medicine  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazufumi","family":"Haino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Niigata University Graduate School of Medical and Dental Sciences  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