{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:28:10Z","timestamp":1740126490670,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,9]],"date-time":"2017-11-09T00:00:00Z","timestamp":1510185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005297","name":"Medical University of Bia\u0142ystok","doi-asserted-by":"crossref","award":["N\/ST\/ZB\/16\/001\/1129"],"award-info":[{"award-number":["N\/ST\/ZB\/16\/001\/1129"]}],"id":[{"id":"10.13039\/501100005297","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Previous research has described a woman of reproductive age who presented with a vesicouterine fistula (VUF) of 20\u2009months\u2019 duration. The VUF was lined with a metaplastic glandular epithelium containing both estrogen receptors (ER) and progesterone receptors (PR) in abundance. The aim of the present investigation was to evaluate the histology of the VUF canal when exposure to urine of the cellular elements within the fistula was of much shorter duration. A 41\u2010year\u2010old woman who developed a VUF during her third cesarean section was treated with transvesical fistula excision, electrocoagulation, and subsequent attempted hormonal treatment. Later, the patient underwent open surgery fistula repair. Postoperative specimens were subjected to anatomopathological examination together with immunohistochemical staining for ER and PR using monoclonal anti\u2010human antibodies. Herein, we present for the first time detailed microscopic evidence that, at two separate timepoints, the fistulous tract was lined with the endometrium, which covered approximately 80% of the length of the VUF canal. In its intermediate segment, the urothelium formed an additional layer on the surface of the endometrium. At both timepoints, in the columnar epithelial and stromal endometrial cells lining the fistula, both ER and PR were present in abundance. In conclusion, VUF in subjects of reproductive age fulfill criteria for endometriosis. This study provides a rationale for the conservative treatment of VUF consistent with the hormonal treatment of endometriosis.<\/jats:p>","DOI":"10.1111\/jog.13525","type":"journal-article","created":{"date-parts":[[2017,11,9]],"date-time":"2017-11-09T19:28:34Z","timestamp":1510255714000},"page":"341-346","source":"Crossref","is-referenced-by-count":1,"title":["Structural arrangement of vesicouterine fistula revisited: An immunohistochemical study documenting the presence of the endometrium"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9182-8791","authenticated-orcid":false,"given":"Maciej","family":"J\u00f3\u017awik","sequence":"first","affiliation":[{"name":"Department of Gynecology and Gynecologic Oncology Medical University of Bia\u0142ystok  Bia\u0142ystok Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"J\u00f3\u017awik","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Faculty of Medical Sciences University of Warmia and Mazury  Olsztyn Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Koz\u0142owski","sequence":"additional","affiliation":[{"name":"Department of Urologic Oncology and General Urology J\u0119drzej \u015aniadecki Voivodeship Polyclinical Hospital  Bia\u0142ystok Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanis\u0142aw","family":"Sulkowski","sequence":"additional","affiliation":[{"name":"Department of General Pathomorphology Medical University of Bia\u0142ystok  Bia\u0142ystok Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Semczuk","sequence":"additional","affiliation":[{"name":"Second Department of Gynecology Medical University of Lublin  Lublin Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micha\u0142","family":"J\u00f3\u017awik","sequence":"additional","affiliation":[{"name":"Department of Reproductive Health National Research Institute of Mother and Child  Warsaw Poland"},{"name":"Medical Institute State Higher School of Computer Science and Business Administration  \u0141om\u017ca Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,9]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_1","DOI":"10.1159\/000030388"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_1","DOI":"10.1080\/09513590310001651768"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_1","DOI":"10.1159\/000282572"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_1","DOI":"10.1159\/000282613"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_1","DOI":"10.1016\/S0020-7292(00)00247-2"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_1","DOI":"10.1007\/s11255-006-9076-7"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_1","DOI":"10.1016\/S0020-7292(97)02837-3"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1097\/00000478-199512000-00011","article-title":"Postcaesarean section uterovesical fistula lined by persistent intermediate trophoblast","volume":"19","author":"Ismail SM","year":"1995","journal-title":"Am J Surg Pathol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"174.e1","DOI":"10.1016\/j.urology.2004.07.001","article-title":"Vesicocervical fistula: Rare complication of cesarean section demonstrated by magnetic resonance imaging","volume":"65","author":"Dudderidge TJ","year":"2005","journal-title":"Urology"},{"doi-asserted-by":"publisher","key":"e_1_2_6_11_1","DOI":"10.1007\/s00192-007-0311-2"},{"doi-asserted-by":"publisher","key":"e_1_2_6_12_1","DOI":"10.1097\/01.AOG.0000281670.94265.5c"},{"key":"e_1_2_6_13_1","first-page":"989","article-title":"Conservative management of vesicouterine fistula. A report of 2 cases","volume":"48","author":"Ravi B","year":"2003","journal-title":"J Reprod Med"},{"key":"e_1_2_6_14_1","first-page":"102","article-title":"Conservative management of traumatic vesico\u2010cervical fistula (a case report)","volume":"33","author":"Varawalla NY","year":"1987","journal-title":"J Postgrad Med"},{"doi-asserted-by":"publisher","key":"e_1_2_6_15_1","DOI":"10.1016\/S0301-2115(03)00099-X"},{"doi-asserted-by":"publisher","key":"e_1_2_6_16_1","DOI":"10.1210\/en.2013-1621"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13525","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13525","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T01:23:57Z","timestamp":1695777837000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,9]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/jog.13525"],"URL":"https:\/\/doi.org\/10.1111\/jog.13525","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"type":"print","value":"1341-8076"},{"type":"electronic","value":"1447-0756"}],"subject":[],"published":{"date-parts":[[2017,11,9]]}}}