{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:48:00Z","timestamp":1780591680563,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T00:00:00Z","timestamp":1510790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aimed to identify the radiologic features of uterine cervical adenocarcinoma associated with lobular endocervical glandular hyperplasia (LEGH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed magnetic resonance (MR) images and pathologic findings of eight patients who underwent preoperative MR imaging followed by surgical resection and who were pathologically diagnosed with adenocarcinoma (except for adenocarcinoma <jats:italic>in situ<\/jats:italic>) associated with LEGH. We assessed the following MR findings: multicystic component (MC), solid component (SC), signal intensity of SC on diffusion\u2010weighted imaging (DWI) and the apparent diffusion coefficient (ADC) map, and radiological stage (r\u2010stage) based on the FIGO classification. A pathologist reevaluated the pathological stage (p\u2010stage) according to the FIGO classification. We correlated the MR findings with the pathologic features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight patients were classified into the following three types based on the MR findings: type A, MC and SC; type B, only SC; and type C, only MC. In the five patients with type A, diffusion restriction (DR) was seen on DWI and the ADC map. In 80% of type A cases, the r\u2010stage matched the p\u2010stage. In the one patient with type B, DR was not seen on DWI or the ADC map, and the r\u2010stage matched the p\u2010stage. In the remaining type C cases, DR was not seen on DWI or the ADC map, and the r\u2010stage was underestimated compared with the p\u2010stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>On MR imaging, the most common type of adenocarcinoma with LEGH is type A; type C is difficult to diagnose as carcinoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13528","type":"journal-article","created":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T11:18:36Z","timestamp":1510831116000},"page":"312-322","source":"Crossref","is-referenced-by-count":20,"title":["Uterine cervical adenocarcinoma associated with lobular endocervical glandular hyperplasia: Radiologic\u2013pathologic correlation"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0786-7531","authenticated-orcid":false,"given":"Ayumi","family":"Ohya","sequence":"first","affiliation":[{"name":"Department of Radiology Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiho","family":"Asaka","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Shinshu University Hospital  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunari","family":"Fujinaga","sequence":"additional","affiliation":[{"name":"Department of Radiology Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masumi","family":"Kadoya","sequence":"additional","affiliation":[{"name":"Department of Radiology Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,16]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Would Health Organization Classification of Tumors of Female Reproductive Organs","author":"Kurman RJ","year":"2014"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.03.044"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.162.3.8109515"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2004.08.013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.204.1.9205220"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199908000-00005"},{"key":"e_1_2_6_8_1","first-page":"1287","article-title":"Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasia of the uterine cervix: multicenter study of clinicopathology and magnetic resonance imaging findings","volume":"21","author":"Takatsu A","year":"2011","journal-title":"Int J Gynecol Obstet"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213434.91868.b0"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.01174.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-014-0323-6"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2008.12.002"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-013-1417-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000229"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2016.08.008"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13528","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T01:23:52Z","timestamp":1695777832000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,16]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/jog.13528"],"URL":"https:\/\/doi.org\/10.1111\/jog.13528","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,16]]}}}