{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T07:09:10Z","timestamp":1781680150349,"version":"3.54.5"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T00:00:00Z","timestamp":1513209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We evaluated whether maintenance tocolysis (intravenous ritodrine hydrochloride and\/or magnesium sulfate) was effective in cases of spontaneous preterm labor with intact membranes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and thirty preterm labor patients who reached 36\u2009weeks of gestation by maintenance tocolysis were selected. Immediate delivery (ID) after ceasing maintenance tocolysis was defined as an \u2018effective case\u2019. The correlated factors between ID and no immediate delivery (NID) were statistically analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six patients delivered &lt; two\u2009days after ceasing maintenance tocolysis (27.7%) and were defined as effective cases. Multiple logistic regression analysis revealed that amniotic fluid interleukin\u20108 at admission (\u2265 2.3\u2009ng\/mL; odds ratio [OR] 5.6, 95% confidence interval [CI] 2.1\u201317.6; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), pre\u2010pregnancy body mass index (\u2264 21.4; OR 5.3, 95% CI 2.0\u201316.2; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and cerclage (OR 3.6, 95% CI 1.1\u201311.8; <jats:italic>P<\/jats:italic>\u2009=\u20090.028) were independent factors correlated with ID (&lt; 2\u2009days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Maintenance tocolysis may be effective in limited cases with mild intra\u2010amniotic inflammation, in lean women and in cerclage cases. Maintenance tocolysis should be ceased in cases without these clinical factors when clinical symptoms disappear.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13547","type":"journal-article","created":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T09:58:42Z","timestamp":1513245522000},"page":"397-407","source":"Crossref","is-referenced-by-count":13,"title":["In which preterm labor\u2010patients is intravenous maintenance tocolysis effective?"],"prefix":"10.1111","volume":"44","author":[{"given":"Satoshi","family":"Yoneda","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Toyama  Toyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Yoneda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Toyama  Toyama 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