{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T11:53:21Z","timestamp":1778846001371,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T00:00:00Z","timestamp":1516665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dienogest is a fourth\u2010generation progestin that is used for the treatment of endometriosis. We report a case of premenstrual mood changes in a patient with schizophrenia who was unresponsive to conventional treatment but successfully managed with dienogest. A 37\u2010year\u2010old Japanese woman with schizophrenia was referred to our hospital and diagnosed with premenstrual exacerbation of schizophrenia or coexisting premenstrual dysphoric disorder with schizophrenia. She had already taken maximal doses of selective serotonin reuptake inhibitors and combined oral contraceptives produced intolerable side effects. Gonadotropin\u2010releasing hormone agonist treatment was effective but was not suitable for long\u2010term use. Dienogest was initiated to treat pelvic endometriosis and produced subsequent improvements in mental status. The patient was able to return to work and did not indicate any adverse effects. This case suggests that dienogest may be useful for managing premenstrual mood changes in patients with schizophrenia, that it can be safely administered over long periods of time.<\/jats:p>","DOI":"10.1111\/jog.13578","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T05:36:36Z","timestamp":1516685796000},"page":"797-800","source":"Crossref","is-referenced-by-count":4,"title":["Treatment of premenstrual mood changes in a patient with schizophrenia using dienogest: A case report"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1271-9082","authenticated-orcid":false,"given":"Yasuhiko","family":"Kamada","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"},{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama University  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3564-1284","authenticated-orcid":false,"given":"Sayoko","family":"Kotani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"},{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama University  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Masuyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"},{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama University  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000140686.66212.1e"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60527-9"},{"key":"e_1_2_6_5_1","first-page":"CD001396","article-title":"Selective serotonin reuptake inhibitors for premenstrual syndrome","volume":"6","author":"Marjoribanks J","year":"2013","journal-title":"Cochrane Database Syst 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