{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:32:10Z","timestamp":1792809130845,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T00:00:00Z","timestamp":1530748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare the efficacy between dienogest and levonorgestrel\u2010releasing intrauterine system (LNG\u2010IUS) after laparoscopic surgery for endometriosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 285 women were diagnosed as endometriosis by laparoscopy between 2011 and 2015. Patients were grouped into no treatment (<jats:italic>n<\/jats:italic> = 83), treatment with dienogest (<jats:italic>n<\/jats:italic> =130) and treatment with LNG\u2010IUS (<jats:italic>n<\/jats:italic> =72) after laparoscopic surgery. The changes of the pain scores were checked at 6, 12 and 24 months after the surgery, and the rates of disease recurrence and treatment discontinuation rate were determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The participants' mean age was 38.9 years (range 21\u201354 years). The mean age of LNG\u2010IUS group (43.7 years) was significantly higher than the no treatment and dienogest groups (39.3 vs 33.9 years, respectively). At 6 and 12 months, the median pain scores in treatment (dienogest and LNG\u2010IUS) groups were significantly lower than control group. Both treatment groups had significantly lower recurrence rate than control group (3.8% and 9.7%, respectively, vs 32.5%, <jats:italic>P<\/jats:italic> =0.001). No significant difference was found in the recurrence rate between the two treatment groups (<jats:italic>P<\/jats:italic> =0.461). Patients in the LNG\u2010IUS group showed lower rate of discontinuation due to complication (27.8%) than those in dienogest group (35.6%, <jats:italic>P<\/jats:italic> =0.010).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LNG\u2010IUS treatment in the patients with endometriosis is effective for postoperative pain control and preventing recurrence, however, the LNG\u2010IUS group is older, it is difficult to compare the efficacy between dienogest and LNG\u2010IUS in present study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13703","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T09:41:17Z","timestamp":1530783677000},"page":"1779-1786","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Comparison of the efficacy of diegnogest and levonorgestrel\u2010releasing intrauterine system after laparoscopic surgery for endometriosis"],"prefix":"10.1111","volume":"44","author":[{"given":"Ki H.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Chungnam National University Hospital  Deajeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye W.","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chungnam National University Hospital  Deajeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo Y.","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chungnam National University Hospital  Deajeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung H.","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chungnam National University Hospital  Deajeon South 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Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heon J.","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chungnam National University Hospital  Deajeon South 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