{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:33:03Z","timestamp":1767166383833,"version":"build-2238731810"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T00:00:00Z","timestamp":1546819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Compare the effectiveness of administration of different doses of rectal misoprostol before cesarean section to reduce intra\u2010 and postoperative blood loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A double\u2010blind randomized clinical trial including 453 term pregnant woman scheduled for elective cesarean section where participants received either 200\u2010, 400\u2010 or 600\u2010\u03bcg misoprostol rectally before cesarean section. Study medications were administered after catheter insertion and shortly before skin incision. Primary outcome measures were intraoperative blood loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The intraoperative blood loss was higher in patients who received 200\u2010\u03bcg misoprostol (464.6 \u00b1 143.1 mL) than those who received 400 or 600 \u03bcg, yet, no statistical difference was found between the 400\u2010 (359.3 \u00b1 120.9 mL) and 600\u2010\u03bcg groups (330.8 \u00b1 133.8 mL). The incidence of side effects as fever and chills increases with increasing the dose of misoprostol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Rectal administration of misoprostol for the prevention of post\u2010partum hemorrhage and decreasing intraoperative blood loss during caesarian section is a good alternative to other uterotonics. Yet, the best dose to be used needs further research to be agreed upon.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.13883","type":"journal-article","created":{"date-parts":[[2019,1,8]],"date-time":"2019-01-08T22:33:19Z","timestamp":1546986799000},"page":"585-591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>RETRACTED:<\/i>\n                    Comparison between 200, 400 and 600 microgram rectal misoprostol before cesarian section: A randomized clinical trial"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1221-9600","authenticated-orcid":false,"given":"Mohamed","family":"Sweed","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mourad","family":"El\u2010Said","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amgad","family":"Abou\u2010Gamrah","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2007.08.025"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17120-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(93)90047-G"},{"key":"e_1_2_7_5_1","first-page":"1039","article-title":"Clinical management guidelines for obstetrician\u2010gynecologists number 76, October 2006: Postpartum hemorrhage","volume":"108","author":"ACOG Practice Bulletin","year":"2006","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05835-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.1.31"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2005.10.001"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01479-X"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2004.02.011"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.02.019"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00711.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69522-6"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2007.09.012"},{"key":"e_1_2_7_15_1","first-page":"87","article-title":"Prevention of postpartum hemorrhage: Options for home births in rural Ethiopia","volume":"13","author":"Prata N","year":"2009","journal-title":"Afr J Reprod Health"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02807.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(03)00174-1"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.08.055715"},{"key":"e_1_2_7_19_1","first-page":"540","article-title":"Amniotic fluid volume assessment with the four\u2010quadrant technique at 36\u201042 weeks' gestation","volume":"32","author":"Phelan JP","year":"1987","journal-title":"J Reprod Med"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2006.05.031"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.11.009"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2012.01869.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-9668.107277"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12464"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2012.03.038"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.03.015"},{"key":"e_1_2_7_27_1","first-page":"1410","article-title":"Postpartum haemorrhage: prevention","volume":"2011","author":"Chelmow D","year":"2011","journal-title":"BMJ Clin Evid"},{"key":"e_1_2_7_28_1","first-page":"229","article-title":"Different doses of sublingual misoprostol versus methylergometrine for the prevention of atonic postpartum haemorrhage","volume":"1","author":"Soltan MH","year":"2007","journal-title":"Int J Health Sci (Qassim)"}],"updated-by":[{"DOI":"10.1111\/jog.15874","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"record-id":"50939"},{"DOI":"10.1111\/jog.15874","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000}}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.13883","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.13883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:34:13Z","timestamp":1705538053000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.13883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,7]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/jog.13883"],"URL":"https:\/\/doi.org\/10.1111\/jog.13883","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,7]]},"assertion":[{"value":"2018-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}