{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:34:22Z","timestamp":1793136862390,"version":"4.5.0"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T00:00:00Z","timestamp":1557964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Prenatal diagnostic testing by chorionic villus sampling (CVS) is sometimes recommended for women with twin pregnancies. However, few studies have compared the outcomes between twins with CVS and control twins without intervention. This study aimed to compare the obstetrical outcomes of CVS in twin pregnancies and those in non\u2010intervention twin pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>First\u2010trimester transabdominal CVS was performed on dichorionic\u2010diamniotic twins (<jats:italic>n<\/jats:italic>\u2009=\u200954; Group 1) between December 2006 and January 2017 at the Department of Obstetrics and Gynecology at our hospital, and the data were retrospectively analyzed. CVS risks were evaluated by comparing obstetrical outcomes with those of a control population of 155 dichorionic\u2010diamniotic twins without intervention (Group 2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The difference in the overall fetal loss rate (Group 1, 7.4% vs Group 2, 3.9%; <jats:italic>P<\/jats:italic>\u2009=\u20090.287) between the two groups was not statistically significant. The miscarriage rate, defined as delivery at &lt;24 gestational weeks, and early preterm delivery, defined as delivery at &lt;34 gestational weeks, were not significant between the groups (miscarriage: Group 1, 5.6% vs Group 2, 3.2%; <jats:italic>P<\/jats:italic>\u2009=\u20090.428; early preterm delivery: Group 1, 11.1% vs Group 2, 9.0%; <jats:italic>P<\/jats:italic>\u2009=\u20090.788). The mean gestational age at delivery, birth weights and neonatal intensive care unit admission rate were not statistically significant between the groups. Thus, the overall fetal loss rate and obstetrical outcomes of Group 1 were comparable with those of Group 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In conclusion, the overall obstetrical outcomes were not significantly different between twins with CVS and control twins with the advantage of enabling early decision\u2010making about selective feticide in twins with CVS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13993","type":"journal-article","created":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T04:53:22Z","timestamp":1558068802000},"page":"1466-1471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Obstetrical outcomes after first\u2010trimester chorionic villus sampling in twin pregnancies: A retrospective case\u2013control study"],"prefix":"10.1111","volume":"45","author":[{"given":"Mi S.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology CHA Bundang Medical Center  Seongnam\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunhee","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology CHA Bundang Medical Center  Seongnam\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo B.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology CHA Bundang Medical Center  Seongnam\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myoung J.","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology CHA Bundang Medical Center  Seongnam\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukho","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology CHA Bundang 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