{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T20:36:53Z","timestamp":1767904613060,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:00:00Z","timestamp":1559433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We evaluated the ability of fetal neurosonography and magnetic resonance imaging (MRI) to asses callosal anomalies (CA) and associated cranial malformations. We also aimed to determine the long\u2010term prognosis of the cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010six cases of CA diagnosed combined with neurosonography and MRI between January 2012 and October 2017 were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventeen of 36 fetuses were diagnosed complete agenesis of corpus callosum (CACC) (47.2%), 9 had partial agenesis of corpus callosum (PACC) (25%) and 10 was dysgenesis of the corpus callosum (DCC) (27.2%) at ultrasonography (US) examination. Fetal MRI reported 16 of cases as CACC (44.4%), 11 PACC (30.5%) and nine (25%) DCC. The overall consistency between neurosonography and MRI in the definition of CA were 91% of cases. Sulcation anomalies were present in 9 cases in the US (25%) and 11 cases in MRI (30.4%). Seven of cases showed posterior fossa abnormalities in the US (19.4%) and eight cases in MRI (22.1%). Neonatal MRI added new findings to fetal MRI and neurosonography including grade\u20101 intraventricular hemorrhage and periventricular leukomalacia in two cases (12.5%). Eighteen cases were terminated (50%), 17 cases were followed up and mean follow up interval was 39\u2009\u00b1\u20095.1\u2009months. The neurologic outcome was abnormal in seven (41.7%) patients. Presence of associated brain anomalies worsened the prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Fetal neurosonography has a comparable performance with MRI in the diagnosis of CA and associated anomalies. It should be used in collaboration with MRI to achieve accurate diagnosis which is crucial for counseling.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.13995","type":"journal-article","created":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T06:56:51Z","timestamp":1559545011000},"page":"1472-1478","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Utilization of neurosonography for evaluation of the corpus callosum malformations in the era of fetal magnetic resonance imaging"],"prefix":"10.1111","volume":"45","author":[{"given":"Gurcan","family":"Turkyilmaz","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tugba","family":"Sarac Sivrikoz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emircan","family":"Erturk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nahit","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sonomed Radiology Center  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burak","family":"Tatl\u0131","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birsen","family":"Karaman","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcven","family":"Toksoy","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130brahim H.","family":"Kalelioglu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recep","family":"Has","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atil","family":"Yuksel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit Istanbul University Istanbul Faculty of Medicine  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32418"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000120229"},{"key":"e_1_2_7_4_1","first-page":"337","article-title":"Neurodevelopment after prenatal diagnosis of isolated agenesis of the corpus callosum: An integrative review","volume":"206","author":"Sotiridias A","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3909"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.08010042.x"},{"key":"e_1_2_7_7_1","first-page":"92","article-title":"Four steps in diagnosing complete agenesis of the corpus callosum in prenatal life","volume":"37","author":"Wiechec M","year":"2016","journal-title":"Ultraschall Med"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00512.x"},{"key":"e_1_2_7_9_1","first-page":"131","volume-title":"MRI of the Fetal Brain\u2010Normal Development and Cerebral Pathologies","author":"Garel C","year":"2004"},{"key":"e_1_2_7_10_1","volume-title":"Ages&StagesQuestionnaires\u00ae (ASQ\u20103\u2122). 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