{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:44:09Z","timestamp":1757313849072,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T00:00:00Z","timestamp":1566172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Adequately powered, randomized controlled studies evaluating efficacy and safety of advanced bipolar energy devices in gynecologic laparoscopic surgery are very few. We aimed to compare the two most commonly used devices in total laparoscopic hysterectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This randomized controlled trial was carried out in the department of obstetrics and gynecology in an education and research hospital. One hundred thirty\u2010two women who underwent total laparoscopic hysterectomy for benign indications were included. Women with age younger than 18\u2009years, suspected malignancy, stage 3\u20134 endometriosis and cervical\/intraligamentary leiomyoma were excluded. Patients were randomized preoperatively to LigaSure or Articulating Enseal. One experienced surgeon performed all operations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LigaSure was used in 67 patients and Enseal was used in 65 patients. Primary outcomes of the study were operative time (time from start of sealing and transection of the round ligament until completion of colpotomy) and total operative time (time from skin incision to skin closure). Secondary outcomes were intraoperative blood loss (blood lost during operative time period) and perioperative complications. Operative time was significantly shorter in LigaSure group (<jats:italic>P<\/jats:italic> = 0.001). Total operative time, intraoperative blood loss and perioperative complications were similar. When two groups were further classified according to uterine weight taking 300\u2009g as cut\u2010off value, operative time was significantly shorter in LigaSure group in both subgroups (<jats:italic>P<\/jats:italic> = 0.003 and <jats:italic>P<\/jats:italic> = 0.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LigaSure use in total laparoscopic hysterectomy shortens operative time when compared with Enseal; without an apparent increase in intraoperative blood loss and perioperative complications. On the other side, total operative time remains unaffected.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14096","type":"journal-article","created":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T08:50:32Z","timestamp":1566204632000},"page":"2220-2227","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of the efficacy and safety of two advanced vessel sealing technologies in total laparoscopic hysterectomy"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4243-7097","authenticated-orcid":false,"given":"Burcu","family":"Aykan Yuksel","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Saglik Bilimleri University, Antalya Education and Research Hospital  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burak","family":"Karadag","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saglik Bilimleri University, Antalya Education and Research Hospital  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baris","family":"Mulayim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saglik Bilimleri University, Antalya Education and Research Hospital  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gmit.2017.08.002"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.02.012"},{"key":"e_1_2_7_4_1","first-page":"193","article-title":"Consistency and sealing of advanced bipolar tissue sealers","volume":"8","author":"Chekan EG","year":"2015","journal-title":"Med Dev Evid 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