{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:26:50Z","timestamp":1790810810120,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T00:00:00Z","timestamp":1570924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study aimed to conduct a comprehensive analysis of clinical studies on acupuncture treatment for breast cancer\u2010related lymphedema (BCRL), so as to explore the efficacy and safety of acupuncture treatment and provide evidence for the clinical decision\u2010making. Public databases, mainly including China Academic Journals Full\u2010text Database, Database of Chinese Sci\u2010Tech Journal, Wanfang, PubMed, Embase and the Cochrane Library, from the establishment of databases to December 2018 were searched for randomized controlled trials (RCT) of acupuncture for BCRL. Clinical RCT on the treatment of BCRL with acupuncture combined with drugs or functional exercise were enrolled for the analysis. Bias risk and quality were assessed by two investigators according to the\n                    <jats:italic>Cochrane Handbook<\/jats:italic>\n                    5.1.0 standard, and the\n                    <jats:sc>Revman<\/jats:sc>\n                    5.3 software was used for meta\u2010analysis. A total of 13 studies were enrolled, comprising 747 patients (377 in the treatment group and 370 in the control group). The results of meta\u2010analysis showed that acupuncture intervention could improve the total effective rate for the treatment of BCRL (odds ratio = 4.62; 95% confidence interval 2.61\u20138.17). Recent studies suggest that acupuncture therapy can alleviate the upper limb swelling and improve the subjective pain and discomfort in patients with BCRL, regardless of the control intervention used. However, the number of high\u2010quality RCT is low. Moreover, most of the studies adopted inconsistent efficacy indicators. Hence, additional blinded, large\u2010sample, randomized, well\u2010controlled studies with objective and uniform efficacy indicators are needed, especially in China, to confirm the findings.\n                  <\/jats:p>","DOI":"10.1111\/jog.14122","type":"journal-article","created":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T21:05:32Z","timestamp":1571000732000},"page":"2307-2317","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Acupuncture therapy for breast cancer\u2010related lymphedema: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"45","author":[{"given":"Wenzhen","family":"Hou","sequence":"first","affiliation":[{"name":"Department of Acupuncture Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Pei","sequence":"additional","affiliation":[{"name":"Department of Acupuncture Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafang","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Manipulation Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Central Laboratory Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Acupuncture Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Acupuncture Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Manipulation Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of TCM WUXI Higher Health Vocational Technology School  Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Central Laboratory Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Acupuncture Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,13]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"CRUK. Breast cancer incidence.2017. [Cited 27 March 2018]. Available from URL:http:\/\/www.cancerresearchuk.org\/health\u2010professional\/cancer\u2010)statistics\/statistics\u2010by\u2010cancer\u2010type\/breast\u2010cancer"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70076-7"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-005-0810-y"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9710-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2014.06.004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010915)92:6<1368::AID-CNCR1459>3.0.CO;2-9"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2012.05.003"},{"key":"e_1_2_7_9_1","first-page":"37","article-title":"Effect of bloodletting and cupping for the treatment of breast cancer\u2010related lymphedema","volume":"23","author":"Jiang X","year":"2008","journal-title":"J Nurs 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