{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T16:52:33Z","timestamp":1778345553772,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T00:00:00Z","timestamp":1581033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To examine attitudes toward preimplantation genetic testing for aneuploidy (PGT\u2010A) in patients with recurrent pregnancy loss (RPL) because it has been performed worldwide in spite of little evidence regarding whether it can improve the live birth rate and prevent miscarriage. There has been no study to examine attitudes toward PGT\u2010A in patients with RPL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a cross\u2010sectional study that used a questionnaire to examine attitudes toward PGT\u2010A, the desire for PGT\u2010A and the factors associated with this desire in 386 patients with RPL between November 2014 and January 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 25.1% of patients desired PGT\u2010A and 35.2% answered that they knew about it. Regarding the reasons for wanting PGT\u2010A, 42.3% thought that it would insure a live birth and with complete case analysis, showed that the patients' wish for PGT\u2010A as a means of giving live birth was affected by their IVF\u2010ET history (adjusted odds ratio 2.7, 95% CI 1.2\u20137.2) and whether they had any knowledge of PGT\u2010A (2.4, 1.1\u20135.3). Those with a higher total family income (3.5, 1.2\u201310.1) and a previous IVF\u2010ET (4.6, 2.0\u201310.3) tended to want PGT\u2010A as a means of avoiding miscarriage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The majority had no opinion or a poor knowledge of PGT\u2010A. More patients who self\u2010assessed as knowing about PGT\u2010A or who had undergone IVF\u2010ET had the above type of misunderstanding. Accurate and up\u2010to\u2010date information from facilities different from those in which PGT\u2010A is performed is necessary before reaching a decision on PGT\u2010A.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14212","type":"journal-article","created":{"date-parts":[[2020,2,8]],"date-time":"2020-02-08T00:09:30Z","timestamp":1581120570000},"page":"567-574","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Attitudes toward preimplantation genetic testing for aneuploidy among patients with recurrent pregnancy loss in Japan"],"prefix":"10.1111","volume":"46","author":[{"given":"Eri","family":"Takeda","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Sugiura\u2010Ogasawara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Ebara","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Health Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamao","family":"Kitaori","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinobu","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Yoshihara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University, Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,7]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"European Society for Human Reproduction and Embryology(ESHRE) early pregnancy guideline development group. 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