{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:30:46Z","timestamp":1792467046836,"version":"4.5.0"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:00:00Z","timestamp":1592179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Approximately 10% of female athletes have a history of stress fractures, which most commonly occur between the ages of 16 and 17\u2009years old.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We investigated whether tartrate\u2010resistant acid phosphatase 5b (TRACP\u20105b), which is a bone resorption marker, can serve as a valid predictor of stress fractures in female athletes in their teens and 20s.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three hundred and sixteen elite female athletes were recruited between 2013 and 2015. Serum TRACP\u20105b and various hormones were examined in blood samples. The serum TRACP\u20105b level was compared between athletes with and without stress fractures within 3\u2009months after the initial collection of their blood samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 316 athletes were divided into two age groups: 13\u201319\u2009years old and 20\u201329\u2009years old. Thirty\u2010six athletes (11.4%) experienced new stress fractures within 3\u2009months after the initial collection of their blood samples. The median serum TRACP\u20105b level was significantly higher in teenage athletes with new stress fractures than in teenage athletes without new stress fractures. In univariate logistic regression analysis, the Z\u2010score of serum TRACP\u20105b was a significant predictive factor of stress fractures in teenage athletes only (odds ratio: 1.87; 95% CI: 1.31\u20132.66; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0012).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For teenage female athletes, TRACP\u20105b is a predictor of the risk of stress fractures, and measuring TRACP\u20105b levels may be useful to prevent stress fractures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14256","type":"journal-article","created":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T08:25:00Z","timestamp":1592209500000},"page":"1436-1442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship between tartrate\u2010resistant acid phosphatase 5b and stress fractures in female athletes"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6952-3879","authenticated-orcid":false,"given":"Sayaka","family":"Nose\u2010Ogura","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology The University of Tokyo  Tokyo Japan"},{"name":"Sports Medical Center Japan Institute of Sports Sciences  Tokyo Japan"},{"name":"Department of Obstetrics and Gynecology University of Toyama  Toyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6942-3018","authenticated-orcid":false,"given":"Osamu","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kitasato University School of Medicine  Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiko","family":"Dohi","sequence":"additional","affiliation":[{"name":"Sports Medical Center Japan Institute of Sports Sciences  Tokyo 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