{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:24:28Z","timestamp":1762431868996,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,19]],"date-time":"2020-07-19T00:00:00Z","timestamp":1595116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2016YFC1000205"],"award-info":[{"award-number":["2016YFC1000205"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To explore the ability of anti\u2010M\u00fcllerian hormone and antral follicle count to predict cumulative live birth and clinical pregnancy in the first complete ovarian stimulation cycle among patients from POSEIDON (Patient\u2010Oriented Strategies Encompassing IndividualizeD Oocyte Number) groups 3\u20134.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single\u2010center retrospective study was conducted on 260 patients in POSEIDON groups 3\u20134 (antral follicle count &lt;5 and\/or anti\u2010M\u00fcllerian hormone &lt;1.2\u2009ng\/mL) who first underwent complete <jats:italic>in vitro<\/jats:italic> fertilization\/intracytoplasmic sperm injection cycles between January 2016 and June 2018. The main outcomes were cumulative live birth rate and cumulative clinical pregnancy rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 260 patients, 113 (43.5%) achieved clinical pregnancy and 82 (31.5%) achieved live birth in their first complete ovarian stimulation cycles. With multivariate regression analysis, age and antral follicle count were significantly correlated with cumulative clinical pregnancy, whereas age and anti\u2010M\u00fcllerian hormone were significantly associated with cumulative live birth. Receiver operating characteristic curve analysis demonstrated that age had the highest accuracy for the prediction of cumulative treatment outcomes. The optimal cut\u2010off value of age was 40.5 and that of antral follicle count was 2.5 for predicting cumulative clinical pregnancy. The optimal cut\u2010off value of age was 36.5 and that of anti\u2010M\u00fcllerian hormone was 0.725 for predicting cumulative live birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings indicate that anti\u2010M\u00fcllerian hormone is a better predictor of cumulative live birth than antral follicle count, independent of age, in the first complete ovarian stimulation cycle of <jats:italic>in vitro<\/jats:italic> fertilization\/intracytoplasmic sperm injection among patients in POSEIDON groups 3\u20134.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14269","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T01:46:15Z","timestamp":1595209575000},"page":"1801-1808","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["<scp>Anti\u2010M\u00fcllerian<\/scp> hormone and antral follicle count differ in their ability to predict cumulative treatment outcomes of the first complete ovarian stimulation cycle in patients from <scp>POSEIDON<\/scp> groups 3 and 4"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6515-7453","authenticated-orcid":false,"given":"Luxin","family":"Liu","sequence":"first","affiliation":[{"name":"Reproductive Medicine Center The First Affiliated Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Reproductive Medicine The First Affiliated Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Canquan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center The First Affiliated Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Reproductive Medicine The First Affiliated Hospital, Sun Yat\u2010Sen University  Guangzhou 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