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H\u2010Scores indicating the staining intensity for ER\u03b1, Bcl\u20102 and NF\u2010\u03baB P65 in the glandular epithelium and stroma were measured separately. Apoptotic cells were detected with the use of the dUTP nick\u2010end labeling (TUNEL) assay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bcl\u20102 was expressed in the cytoplasm of glandular epithelial cells, whereas ER\u03b1 was expressed in the nuclei of both glandular epithelial and stromal cells. NF\u2010\u03baB P65 was observed in the cytoplasm of both glandular epithelial and stromal cells. The H\u2010scores for Bcl\u20102 in the endometrial glands significantly higher in the endometriosis polyp group than in the non\u2010endometriosis polyp group. The H\u2010scores for ER\u03b1 in both stromal and glandular epithelial cells were significantly higher in the endometriosis polyp group than in the non\u2010endometriosis polyp group. The H\u2010scores for Bcl\u20102 and ER\u03b1 were positively correlated in all of the women examined. Apoptotic cells in the endometriosis polyp group were significantly less than that of the non\u2010endometriosis polyp group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There expression levels of Bcl\u20102 and ER\u03b1, both of which were significantly increased in the polyps of endometriosis patients compared to those of patients without endometriosis, were positively correlated. These results suggested that imbalanced apoptosis secondary to abnormally high ER\u03b1 expression was responsible for the high prevalence of polyps in endometriosis patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14370","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T03:33:26Z","timestamp":1594611206000},"page":"1819-1826","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Immunohistochemical expression of estrogen receptor \u03b1, Bcl\u20102 and <scp>NF\u2010\u03baB P65<\/scp> in the polyps of patients with and without endometriosis"],"prefix":"10.1111","volume":"46","author":[{"given":"Rufang","family":"Jiang","sequence":"first","affiliation":[{"name":"Center of Reproductive Medicine The First Affiliated Hospital of Guangxi Medical University  Nanning 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