{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T20:46:19Z","timestamp":1694119579285},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We investigated the effects of uterine cavity lavage using hypochlorous acid water (HClO) on preventing postoperative intrauterine infection after microwave endometrial ablation (MEA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four hundred and eleven consecutive patients were enrolled in this study. The patients were divided into two groups: 214 cases in 2014\u20132016 with disinfection using povidone\u2010iodine antiseptic solution alone (group A) and 197 cases in 2017\u20132019 with additional intrauterine douche using HClO (group B). HClO was used at a concentration of 200\u2009ppm of residual chlorine. One gram of Ceftriaxone Sodium Hydrate was administered by drip infusion during MEA in both groups. Oral antibiotics were administered after MEA only in group A but not in group B.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean patient age (mean\u2009\u00b1\u2009SD; years old) was 44.5\u2009\u00b1\u20094.6 in group A and 44.8\u2009\u00b1\u20095.4 in group B, and mean operation time (min) was 30.4\u2009\u00b1\u200919.1 in group A and 34.4\u2009\u00b1\u200922.6 in group B, respectively. Neither were significantly different between groups. The combined ablation techniques i.e. transcervical microwave myolysis and transcervical microwave adenomyolysis did not increase frequency of infection. Postoperative intrauterine infection cases in group B (8 cases) were significantly lower than those in group A (28 cases) (Chi\u2010square test, <jats:italic>P<\/jats:italic> =\u20090.001). Hysterectomy was performed in three severe intrauterine infection cases in group A, but no cases of severe intrauterine infection was found in group B. No adverse effect of HClO was seen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intrauterine douche using HClO decreases postoperative intrauterine infection after MEA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14471","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T01:25:56Z","timestamp":1600305956000},"page":"2417-2422","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypochlorous acid water prevents postoperative intrauterine infection after microwave endometrial ablation"],"prefix":"10.1111","volume":"46","author":[{"given":"Akira","family":"Tsuda","sequence":"first","affiliation":[{"name":"Sanno Ladies Clinic  Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Kanaoka","sequence":"additional","affiliation":[{"name":"Department of Gynecology Iseikai Hospital  Osaka 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