{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:35:56Z","timestamp":1790631356604,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002951","name":"Dokkyo Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 27\u2010year\u2010old woman, gravida 1, para 0, was transferred to our hospital with acute abdominal pain. Her serum human chorionic gonadotropin level was 60\u2009231 mIU\/mL. Transabdominal ultrasound revealed an echo\u2010free space, and emergency laparoscopy\u2010assisted surgery was performed with a preoperative diagnosis of ruptured ectopic pregnancy. The pelvic cavity was filled with clots, and the peritoneal surface of the uterine fundus was swollen and showed continuous bleeding. The lesion was located on peritoneum and not connected with the uterine cavity. Histological examination of the conceptus showed features of a complete hydatidiform mole. After a mild decrease, hCG levels adversely increased 3\u2009weeks later with multiple lung nodules. With a diagnosis of invasive moles, the patient was administered chemotherapy. This case demonstrates that it is important to recognize the potential of ectopic hydatidiform moles through abdominal pregnancy. This is the first report of an invasive abdominal hydatidiform mole, and hCG monitoring seemed to be essential for gestational trophoblastic neoplasia detection.<\/jats:p>","DOI":"10.1111\/jog.14537","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T10:30:21Z","timestamp":1603189821000},"page":"420-424","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Invasive mole with lung metastasis after an abdominal complete hydatidiform mole treatment"],"prefix":"10.1111","volume":"47","author":[{"given":"Shiho","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Dokkyo Medical University Hospital  Mibu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Dokkyo Medical University Hospital  Mibu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Obayashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Dokkyo Medical University Hospital  Mibu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Kitazawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Dokkyo Medical University Hospital  Mibu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Department of Pathology Dokkyo Medical University Hospital  Mibu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichio","family":"Fukasawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Dokkyo Medical University Hospital  Mibu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.12.3224"},{"key":"e_1_2_6_3_1","first-page":"549","article-title":"Abdominal pregnancy: Current concepts of management","volume":"71","author":"Martin JN","year":"1988","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_4_1","first-page":"329","article-title":"Hydatidiform mole in ectopic pregnancy: Clinical, imaging, pathological and immunohistochemical characteristics","volume":"57","author":"Cortes\u2010Charry R","year":"2012","journal-title":"J Reprod Med"},{"key":"e_1_2_6_5_1","first-page":"297","article-title":"Ectopic gestational trophoblastic disease: A case series review","volume":"57","author":"Hassadia A","year":"2012","journal-title":"J Reprod Med"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12287"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001374"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003566"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(03)90120-2"},{"key":"e_1_2_6_10_1","first-page":"459","article-title":"Diagnostic score for choriocarcinoma and invading hydatidiform mole","volume":"36","author":"Ishizuka N","year":"1984","journal-title":"Nihon Sanka Fujinka Gakkai Zasshi"},{"key":"e_1_2_6_11_1","first-page":"90","volume-title":"The General Rules for Clinical and Pathological Management of Trophoblastic Diseases July 2011 the 3rd edition","year":"2011"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pgp.0000164597.19346.b5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"12542","DOI":"10.1038\/s41598-019-49047-7","article-title":"Genome\u2010wide single nucleotide polymorphism array analysis unveils the origin of heterozygous androgenetic complete moles","volume":"9","author":"Usui H","year":"2019","journal-title":"Sci Rep"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000174583.51617.25"},{"key":"e_1_2_6_15_1","first-page":"26","article-title":"Painful Synostotic pes Valgoplanus","volume":"53","author":"Bedogni C","year":"1964","journal-title":"Chir. 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