{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T20:56:34Z","timestamp":1769720194382,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Andersen\u2013Tawil syndrome (ATS) is a rare hereditary long QT syndrome type 7 caused by a missense mutation in the <jats:italic>KCNJ2<\/jats:italic> gene. ATS is characterized by ventricular arrhythmia, periodic limb paralysis and minor external malformations. Although only three reports of pregnant women with Andersen\u2013Tawil syndrome have been reported to date, no exacerbation of ventricular arrhythmia was observed from pre\u2010partum to delivery in all cases compared to that before pregnancy, and it was suggested that the risk of arrhythmic events from pre\u2010partum to delivery is not high. Unlike these previous reports, we herein present a case of Andersen\u2013Tawil syndrome in which ventricular arrhythmias increased and sustained ventricular tachycardia was developed during labor progression. We also advise caution that pregnant patients with Andersen\u2013Tawil syndrome may have varying times of exacerbation of the arrhythmia, and ventricular arrhythmias may be associated with painful uterine contractions.<\/jats:p>","DOI":"10.1111\/jog.14553","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T07:54:37Z","timestamp":1605686077000},"page":"446-451","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Obstetric management of a patient with Andersen\u2013Tawil syndrome: A case report"],"prefix":"10.1111","volume":"47","author":[{"given":"Mai","family":"Inagaki","sequence":"first","affiliation":[{"name":"Comprehensive Reproductive Medicine, Regulation of Internal Environment and Reproduction, Graduate School Tokyo Medical and Dental University  Tokyo 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Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00342-7"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1971.tb06990.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350313"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01216.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joa.2012.08.002"},{"key":"e_1_2_5_7_1","first-page":"e12798","article-title":"Successful treatment of arrhythmia with \u03b2\u2010blocker and flecainide combination in pregnant patients with Andersen\u2013Tawil syndrome: A case report and literature review","author":"Rujirachun P","year":"2020","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"e_1_2_5_8_1","unstructured":"Japanese Circulation Society.Guideline on 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