{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:58:16Z","timestamp":1792040296004,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the prevalence of stress urinary incontinence (SUI) and intrinsic sphincter deficiency (ISD) in women with stage IV pelvic organ prolapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of women with stage IV prolapse who underwent multichannel urodynamic testing. Abdominal leak point pressures (ALPP) and maximum urethral closure pressures (MUCP) were recorded. ISD was defined as ALPP \u226460\u2009cm of water and\/or MUCP \u226420\u2009cm of water. Percentages were used to present the proportion of subjects diagnosed with SUI and ISD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 145 patients met inclusion criteria. Mean age was 69\u2009years; most patients were Caucasian (56%). Eighty\u2010two (56%) patients were found to have SUI on urodynamic testing. Thirty\u2010six (44%) of these were asymptomatic and identified as having occult SUI. Sixteen (19.5%) patients were diagnosed with ISD using ALPP and\/or MUCP. Six (37%) of the ISD patients had at least one MUCP value \u226420\u2009cm of water and 12 (75%) had observed leakage with at least one ALPP value \u226460\u2009cm of water. The number of patients with leakage at ALPP \u226460\u2009cm of water increased with increasing bladder volumes. Five ISD patients (31%) had ALPP \u226460\u2009cm of water at 200\u2009mL, six (37.5%) had ALPP \u226460\u2009cm of water at 300\u2009mL and seven (43.8%) had ALPP \u226460\u2009cm of water at 400\u2009mL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Greater than 50% of patients with stage IV pelvic organ prolapse had SUI on urodynamic testing, and 20% were found to have ISD. Of the patients diagnosed with SUI, 40% were asymptomatic. These findings may assist in counseling and preoperative planning for women with stage IV prolapse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14574","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T07:50:25Z","timestamp":1605685825000},"page":"640-644","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Prevalence of stress urinary incontinence and intrinsic sphincter deficiency in patients with stage <scp>IV<\/scp> pelvic organ prolapse"],"prefix":"10.1111","volume":"47","author":[{"given":"Keila S.","family":"Mu\u00f1iz","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Zucker School of Medicine at Hofstra\/Northwell  New Hyde Park New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie","family":"Pilkinton","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery Zucker School of Medicine at Hofstra\/Northwell  Great Neck New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvey A.","family":"Winkler","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery Zucker School of Medicine at Hofstra\/Northwell  Great Neck New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dara F.","family":"Shalom","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery Zucker School of Medicine at Hofstra\/Northwell  Great Neck New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181f73729"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-201711000-00052"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.04.048"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001920200053"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000057"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00242-9"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.09.104"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2797-3"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","unstructured":"CornellaJ.Intrinsic sphincter deficiency. 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