{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:26:18Z","timestamp":1784751978513,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nasal septal perforation caused by bevacizumab is rarely reported in other cancers such as ovarian cancer and breast cancer, but it has not been reported in cervical cancer. A 48\u2010year\u2010old woman with a medical history of chronic allergic rhinitis was diagnosed stage 4B (T2bN1M0) cervical cancer and paclitaxel and carboplatin along with bevacizumab (triweekly) were administered. After eight courses of chemotherapy, nasal septal perforation was noted. The possibility of nasal septal perforation by bevacizumab was considered by excluding other causes. We report the first case of nasal septal perforation caused by bevacizumab for advanced cervical cancer.<\/jats:p>","DOI":"10.1111\/jog.14589","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T20:30:40Z","timestamp":1607632240000},"page":"833-837","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A case of nasal septal perforation caused by bevacizumab for advanced cervical cancer"],"prefix":"10.1111","volume":"47","author":[{"given":"Yusuke","family":"Taira","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Shimoji","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadaharu","family":"Nakasone","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihisa","family":"Arakaki","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Nakamoto","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wataru","family":"Kudaka","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichi","family":"Aoki","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Graduate School of Medical Science University of the Ryukyus  Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2004.12.005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm988"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-0731"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1104390"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1309748"},{"key":"e_1_2_6_7_1","first-page":"437","article-title":"Bevacizumab\u2010induced bowel perforation","volume":"111","author":"Sliesoraitis S","year":"2011","journal-title":"J Am Osteopath Assoc"},{"key":"e_1_2_6_8_1","first-page":"pii: S0085\u20102538","article-title":"Nephrotoxicity induced by intravitreal vascular endothelial growth factor inhibitors: Emerging evidence","volume":"98","author":"Hanna RM","year":"2019","journal-title":"Kidney Int"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2017.08.012"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12282-011-0255-8"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-012-0236-x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.11-10-1070"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605828"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.12913"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.11-1-85"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.12.0006"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-010-9464-9"},{"key":"e_1_2_6_18_1","first-page":"1124","article-title":"Perforation of the nasal septum: A rare complication of bevacizumab","volume":"29","author":"Bylicki O","year":"2012","journal-title":"Lung"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31817c4296"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-0974"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2017.01.018"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-018-0754-1"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.960388"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.14589","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jog.14589","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.14589","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T15:41:25Z","timestamp":1693755685000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.14589"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,9]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/jog.14589"],"URL":"https:\/\/doi.org\/10.1111\/jog.14589","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,9]]},"assertion":[{"value":"2020-07-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}