{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:38:47Z","timestamp":1780447127439,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T00:00:00Z","timestamp":1608076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the usefulness of the \u2018cosmos pattern\u2019 (CP) on magnetic resonance (MR) images for differentiating between gastric\u2010type mucin\u2010positive lesions (GMPL) and gastric\u2010type mucin\u2010negative lesions (GMNL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study included 131 patients with clinical suspicion of lobular endocervical glandular hyperplasia (LEGH) who underwent pelvic MR imaging and a Pap smear and\/or latex agglutination assay. Differences in MR findings, such as cyst and solid component patterns, cervical location and T1\u2010weighted image (T1WI) signal intensity, were compared between GMPL and GMNL. The diagnostic performances of the findings were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The frequencies of CP (63.1%), upper part (UP) lesions (72.3%) and hypointense area compared with the cervical stroma on T1WI (61.3%) were significantly greater in GMPL than in GMNL (<jats:italic>P<\/jats:italic> &lt;\u20090.05). The sensitivity, specificity, positive predictive value, negative predictive value and odds ratio of the CP for diagnosis of GMPL were 63.1%, 87.9%, 83.7%, 70.7% and 12.4, respectively. In GMNL, a \u2018macrocystic pattern\u2019 was observed in 65.2% of patients; an isointense or hyperintense area on T1WI was observed in 86.4% of patients. The sensitivity was highest (90.8%) when one or more of the following were observed: CP, UP lesion, or hypointense area on T1WI. The specificity was highest (95.5%) when the CP was observed as a hypointense area on T1WI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The CP is a highly specific finding for diagnosis of GMPL. If the CP is observed as a hypointense area compared with the cervical stroma on T1WI, GMPL (i.e., LEGH or gastric\u2010type mucinous carcinoma) should be strongly suspected.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.14602","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T03:46:04Z","timestamp":1608263164000},"page":"745-756","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Usefulness of the \u2018cosmos pattern\u2019 for differentiating between cervical gastric\u2010type mucin\u2010positive lesions and other benign cervical cystic lesions in magnetic resonance images"],"prefix":"10.1111","volume":"47","author":[{"given":"Ayumi","family":"Ohya","sequence":"first","affiliation":[{"name":"Department of Radiology Shinshu University School of Medicine  Matsumoto 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