{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T10:45:22Z","timestamp":1743849922347},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T00:00:00Z","timestamp":1632096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe a new sonographic feature of the C\u2010sign for prenatal diagnosis of jejunal atresia and evaluate its role in prenatal jejunal atresia, particularly preceding bowel dilatation and polyhydramnios.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective study from a tertiary maternal hospital. Patients with prenatal sonographic examination and confirmed small bowel atresia postdelivery were included. All sonographic images were reviewed by two senior sonographers. Comparison of sonographic images between prenatal jejunal and ileal atresia using the C\u2010sign resembles the shape of the entire duodenum and other traditional sonographic features. The control group without bowel atresia was assessed for the presence of the C\u2010sign.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The C\u2010sign and combined bowel dilatation with polyhydramnios were more frequent in jejunal atresia than ileal atresia, but the C\u2010sign can be used to detect jejunal atresia earlier. The C\u2010sign can be more likely to diagnose jejunal atresia in persisting bowel dilatation and polyhydramnios. The C\u2010sign was not reported in any of the control fetuses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The C\u2010sign is a new sonographic feature that can be used to improve the prenatal accuracy and early detection of jejunal atresia. However, further prospective validation is needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15029","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T02:52:57Z","timestamp":1632192777000},"page":"4196-4202","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["New sonographic feature (C\u2010sign) to improve the prenatal accuracy of jejunal atresia"],"prefix":"10.1111","volume":"47","author":[{"given":"Dan","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Ultrasound Guangdong Women and Children Hospital  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwong Ho","family":"Tam","sequence":"additional","affiliation":[{"name":"Ocean Gardens Health Centre Health Bureau  Macau SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiwei","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department 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