{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:05:56Z","timestamp":1791835556330,"version":"4.3.4"},"reference-count":9,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T00:00:00Z","timestamp":1632960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Acute fatty liver of pregnancy (AFLP) is a rare disorder that typically develops in the third trimester. We successfully diagnosed and treated a case of AFLP that developed at 18\u2009weeks' gestation. A 34\u2010year\u2010old woman\u2014gravida 4, para 3\u2014presented with continuous vomiting and abdominal pain and developed convulsive seizures and lost consciousness after transfusion therapy. Cerebral apoplexy was excluded by computed tomography of the brain. Blood tests revealed severe metabolic acidosis, coagulopathy, and leukocytosis, followed by severe hypoglycemia and elevated levels of transaminases and ammonia. The fetus was delivered dead. Whole\u2010body computed tomography showed fatty liver. The patient was diagnosed with AFLP based on the Swansea criteria. AFLP may be a differential diagnosis in the second trimester, and rapid termination should be considered as radical treatment. Starvation may be a risk factor for this disorder.<\/jats:p>","DOI":"10.1111\/jog.15050","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T22:27:33Z","timestamp":1633040853000},"page":"4467-4471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Acute fatty liver of pregnancy at 19\u2009weeks and 0\u2009days of gestation after prolonged hyperemesis gravidarum"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3377-6863","authenticated-orcid":false,"given":"Airi","family":"Komura","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Kanto Rosai Hospital  Kawasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushiro","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kanto Rosai Hospital  Kawasaki 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