{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T06:26:56Z","timestamp":1775284016332,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>We aimed to investigate the incidence of adverse pregnancy outcomes including preterm birth, preeclampsia (PE), and fetal growth restriction (FGR) in pregnant women with COVID\u201019 according to the gestational age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 167 pregnant women who were hospitalized with confirmed COVID\u201019. The patients were divided into three groups according to the time of diagnosis as follows: &lt;12\u2009weeks of gestation (first trimester, <jats:italic>n<\/jats:italic>\u00a0=\u00a010), 12\u201324\u2009weeks of gestation (<jats:italic>n<\/jats:italic>\u00a0=\u00a028), and &gt;24\u2009weeks of gestation (<jats:italic>n<\/jats:italic>\u00a0=\u00a0129). Medical records of the patients were reviewed retrospectively and adverse pregnancy outcomes were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 49 (29.3%) patients had an active COVID\u201019 infection at the time of delivery, while 118 (70.7%) gave birth after the infection was cleared. Twenty\u2010three patients had preterm birth and the gestational age was &lt;34\u2009weeks in only four of these patients. There was no significant difference in the preterm birth, PE, FGR, HELLP syndrome, and gestational diabetes mellitus among the three gestation groups (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.271, 0.394, 0.403, 0.763, and 0.664, respectively). Four (2.39%) patients required intensive care unit stay. Maternal death was seen in only one (0.59%) patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study showed no significant correlation between the gestational age at the time of COVID\u201019 infection and the frequency of adverse pregnancy outcomes such as preterm birth, PE, FGR, and gestational diabetes mellitus. However, further studies are needed to draw a firm conclusion on this topic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15051","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T00:22:47Z","timestamp":1632874967000},"page":"4232-4240","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The effect of gestational age at the time of diagnosis on adverse pregnancy outcomes in women with <scp>COVID<\/scp>\u201019"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9113-9846","authenticated-orcid":false,"given":"G\u00fcltekin Adana\u015f","family":"Ayd\u0131n","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Bursa City Hospital  Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6691-9923","authenticated-orcid":false,"given":"Serhat","family":"\u00dcnal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Bursa City Hospital  Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2021-6311","authenticated-orcid":false,"given":"Hilal G\u00fcls\u00fcm Turan","family":"\u00d6zsoy","sequence":"additional","affiliation":[{"name":"Department of Radiology Bursa City Hospital  Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.01.009"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6915e3"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003873"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12355"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2012.02.023"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaaa030"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M200581200"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0230295"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100446"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.22088"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13317"},{"key":"e_1_2_9_13_1","first-page":"2020","volume-title":"Clinical management of severe acute respiratory infection when novel coronavirus (2019\u2010nCoV) is suspected: interim guidance","author":"World Health Organization","year":"2020"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3233\/XST-200687"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2018.05.004"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002220"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqaa089"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2020.08.018"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/apm.12833"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.055236"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.23134"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-virology-092917-043236"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.04.007"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.22186"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm-2020-0355"},{"key":"e_1_2_9_26_1","first-page":"1","article-title":"COVID\u201019 pandemic effect on early pregnancy: are miscarriage rates altered, in asymptomatic women?","volume":"9","author":"Rotshenker\u2010Olshinka K","year":"2020","journal-title":"Arch Gynecol Obstet"},{"key":"e_1_2_9_27_1","first-page":"391","article-title":"Coronavirus disease 2019 and first\u2010trimester spontaneous abortion: a case\u2010control study of 225 pregnant patients","volume":"224","author":"Cosma S","year":"2020","journal-title":"Am J Obstet Gynecol."},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.23107"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000094734.67990.99"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000092888.63239.54"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.90592.2008"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-017-0316-8"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2004000800017"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000251"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2020.100107"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-015-0624-y"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000437382.03963.88"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16339"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.09.020"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-814823-5.00010-6"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13182"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2020.101826"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25770"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13265"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2020.12.007"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.15051","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jog.15051","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.15051","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T02:56:28Z","timestamp":1693191388000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.15051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,28]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1111\/jog.15051"],"URL":"https:\/\/doi.org\/10.1111\/jog.15051","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,28]]},"assertion":[{"value":"2021-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}