{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T10:57:06Z","timestamp":1783767426418,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Laparoscopic hysterectomy (LH) have been frequently used because of low complication rates and short duration of hospital stay. Elevated intracranial pressure (ICP), a disadvantage of laparoscopic surgery, is caused by the Trendelenburg position (TP) and CO<jats:sub>2<\/jats:sub> pneumoperitoneum (PP). This study aimed to evaluate TP and PP associated changes in ICP by ONSD measurements during LH. The intra\u2010and inter\u2010observer consistency and reliability of ONSD measurements were also investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty patients with were enrolled into this prospective study. ONSD for each patient was measured by three anesthesiologists at T0, T1, T2, and T3 time points. ONSD, mean arterial pressure (MAP), end tidal CO<jats:sub>2<\/jats:sub> (EtCO<jats:sub>2<\/jats:sub>), and arterial blood CO<jats:sub>2<\/jats:sub> partial pressure values (PaCO<jats:sub>2<\/jats:sub>) were measured at T0: baseline, T1: 10\u00a0min after introducing 20\u2009mmHg PP, T2: 10\u00a0min after placing the patient in TP and 15\u2009mmHg PP and, T3: 10\u00a0min after PP deflation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The ONSD measured at T1 (5.97\u2009\u00b1\u20090.49\u2009cm) and T2 (5.95\u2009\u00b1\u20090.57\u2009cm) were higher than T0 (5.63\u2009\u00b1\u20090.53\u2009cm) and T3 (5.72\u2009\u00b1\u20090.47\u2009cm) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). There were no correlations between MAP and ONSD, and also between PaCO<jats:sub>2<\/jats:sub>, EtCO<jats:sub>2<\/jats:sub>, and ONSD measurements at any time points. Inter\u2010observer intraclass correlation coefficient (ICC) values of ONSD measurements by all examiners had moderate (at T1) to good (at T0, T2, T3) reliability. Intra\u2010observer agreements were reasonable for each observer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ONSD measurements increase with CO<jats:sub>2<\/jats:sub>PP and TP in patients undergoing LH. Transorbital sonography is a reliable method to monitor intraoperative changes in ONSDs. This study underlines the need for careful training and the importance of standardization in order to obtain reliable results in the examination technique of ONSD measurements.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15147","type":"journal-article","created":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T05:09:59Z","timestamp":1642655399000},"page":"830-837","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The effect of pneumoperitoneum and Trendelenburg position on optic nerve sheath diameter in patients undergoing laparoscopic hysterectomy"],"prefix":"10.1111","volume":"48","author":[{"given":"Tural","family":"Bayramov","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3295-9999","authenticated-orcid":false,"given":"Banu","family":"Kilicaslan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seda B.","family":"Akinci","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokhan","family":"Boyraz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine Hacettepe University  Ankara 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