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Related data from retrieved articles were summarized in different headings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>VVC has a global distribution and<jats:italic>Candida albicans<\/jats:italic>is the leading cause of infection except for specific patient groups like postmenopausal, diabetic, or immunocompromised women. VVC has a range of clinical presentations, accordingly, its diagnosis should be based on clinical examination coupled with laboratory investigations. The best therapeutic regimen depends on the patient's conditions and the causative agent. Moreover, factors like drug resistance of the causative agents and different mutations in the immunity\u2010related genes could affect the treatment outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>As a globally distributed disease, VVC needs further attention, especially in areas related to the treatment failure and recurrence of the disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15267","type":"journal-article","created":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T02:59:59Z","timestamp":1650509999000},"page":"1546-1560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Vulvovaginal candidiasis: An overview of mycological, clinical, and immunological 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