{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:48:52Z","timestamp":1790894932963,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The objective of this study was to compare neonatal and maternal outcomes among women with two previous cesarean deliveries who undergo trial of labor after two cesarean section (TOLA2C) versus elective repeat cesarean delivery (ERCD). Our primary outcome was neonatal intensive care unit (NICU) admission. Secondary outcomes included APGAR score &lt;7 at 5\u2009min, TOLA2C success rate, uterine rupture, postpartum hemorrhage, maternal blood transfusion, maternal bowel and bladder injury, immediate postpartum infection, and maternal mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study was undertaken at a community medical center from January 1, 2008 to December 31, 2018. Inclusion criteria were women with a vertex singleton gestation at term and a history of two prior cesarean sections. Exclusion criteria included a previous successful TOLA2C, prior classical uterine incision or abdominal myomectomy, placenta previa or invasive placentation, multiple gestation, nonvertex presentation, history of uterine rupture or known fetal anomaly. Maternal and neonatal outcomes were assessed using Fisher exact test and Wilcoxon rank sum test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 793 patients fulfilled study criteria. There were no differences in neonatal intensive care unit admissions or 5\u2010min APGAR scores &lt;7 between the two groups. Sixty\u2010eight percent of women who underwent TOLAC (\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a082) had a successful vaginal delivery. The uterine rupture rate was 1.16% (\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a01) in the TOLA2C group with no case of uterine rupture in the ERCD group. No difference in maternal morbidity was noted between the two groups. No maternal or neonatal mortalities occurred in either group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There was no difference in maternal or neonatal morbidity among patients in our study population with two previous cesarean sections who opted for TOLA2C versus ERCD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.15351","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T19:15:23Z","timestamp":1657134923000},"page":"2528-2533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Trial of labor after two cesarean sections: A retrospective case\u2013control study"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2752-4061","authenticated-orcid":false,"given":"Rebecca","family":"Horgan","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; 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Gynecology Monmouth Medical Center  Long Branch New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred Z.","family":"Abuhamad","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine Eastern Virginia Medical School  Norfolk Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Kawakita","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine Eastern Virginia Medical School  Norfolk Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Graebe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Monmouth Medical Center  Long Branch New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"issue":"2","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1097\/AOG.0b013e3181eeb251","article-title":"ACOG practice bulletin no. 115: vaginal birth after previous cesarean delivery","volume":"116","year":"2010","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000219750.79480.84"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002983"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32394-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1995.tb09060.x"},{"key":"e_1_2_8_7_1","volume-title":"Healthcare cost and utilization project (HCUP) statistical briefs","author":"Pfuntner A","year":"2006"},{"key":"e_1_2_8_8_1","volume-title":"Births: final data for 2018","author":"Martin JHB","year":"2019"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.07.002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.09.028"},{"key":"e_1_2_8_11_1","first-page":"1","article-title":"Vaginal birth after cesarean: new insights","volume":"191","author":"Guise JM","year":"2010","journal-title":"Evid Rep Technol Assess (Full Rep)"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.06.035"},{"issue":"7","key":"e_1_2_8_13_1","first-page":"312","article-title":"Multiple repeat cesarean sections: operative difficulties, maternal complications and outcome","volume":"58","author":"Gasim T","year":"2013","journal-title":"J Reprod Med"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1183638"},{"issue":"29","key":"e_1_2_8_15_1","first-page":"489","article-title":"Indications for and risks of elective cesarean section","volume":"112","author":"Mylonas I","year":"2015","journal-title":"Dtsch Arztebl Int"},{"key":"e_1_2_8_16_1","unstructured":"Healthy Women Healthy Pregnancies Healthy Futures:Action Plan to Improve Maternal Health in America: U.S Department of Health & Human Services; 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