{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T03:03:49Z","timestamp":1778555029389,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the efficacy of intravenous ferric carboxymaltose (IV FCM) for the treatment of iron deficiency anemia (IDA) diagnosed de novo in the third trimester of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Case\u2013control study conducted in pregnant women with IDA newly diagnosed in the third trimester of pregnancy. Women treated with a single IV FCM injection were included as cases and those who received daily 210\u2009g of oral ferrous sulphate (FS) as controls. Controls were matched to cases in a 2:1 ratio by basal hemoglobin (Hb) concentration (\u00b10.5\u00a0g\/dl).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 35 cases and 70 controls were included in the study. The mean Hb concentration level significantly increased after iron treatment in both cases (from 9.3\u00a0\u00b1\u20090.8 to 11.1\u00a0\u00b1\u20090.8\u00a0g\/dl, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.0001) and controls (from 9.6\u00a0\u00b1\u20090.9 to 10.9\u00a0\u00b1\u20091\u00a0g\/dl, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.0001). The rate of women who exceeded the recommended threshold of 11\u2009g\/dl after treatment did not significantly differ between cases (63% (95%CI, 45%\u201379%)) and controls (56% (95%CI, 44%\u201368%)) (<jats:italic>p<\/jats:italic>\u00a0=\u20090.48). Comparison of maternal and neonatal outcomes and adverse effects did not show any significant difference between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that IV FCM and oral FS can be considered equally effective in the treatment of IDA newly detected in the third trimester of pregnancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15558","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T05:23:36Z","timestamp":1674192216000},"page":"1161-1166","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of ferric carboxymaltose for treatment of iron deficiency anemia diagnosed in the third trimester of pregnancy: A case\u2013control study"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9870-5241","authenticated-orcid":false,"given":"Andrea","family":"Busnelli","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"},{"name":"IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Fabiani","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Acerboni","sequence":"additional","affiliation":[{"name":"IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Moretti Montefusco","sequence":"additional","affiliation":[{"name":"IRCCS Humanitas Research Hospital  Milan 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