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After 2\u2009years of postoperative chemotherapy, she developed headache and dizziness, and a suspected metastatic cerebellar mass in left ovary was detected. Pathological analysis of the mass revealed HGSOC, which was removed surgically. Eight months and another 6\u2009months after the surgery, local recurrence was noted; hence, she underwent CyberKnife treatment. After 3\u2009months, cervical spinal cord metastasis was found, evidenced by left shoulder pain. Moreover, meningeal dissemination was present around the cauda equina. Chemotherapy treatment, including bevacizumab, was ineffective and increased lesions were observed. After CyberKnife treatment for the cervical spinal cord metastasis, niraparib was initiated for the meningeal dissemination. The cerebellar lesions and meningeal dissemination improved within 8\u2009months of niraparib treatment. Although meningeal dissemination is challenging to treat, niraparib may be useful in <jats:italic>BRCA<\/jats:italic>\u2010mutated HGSOC.<\/jats:p>","DOI":"10.1111\/jog.15663","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T07:15:42Z","timestamp":1682666142000},"page":"1875-1879","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with <scp><i>BRCA1<\/i><\/scp> mutation"],"prefix":"10.1111","volume":"49","author":[{"given":"Takashi","family":"Nei","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3130-3736","authenticated-orcid":false,"given":"Satoshi","family":"Tamauchi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9456-0468","authenticated-orcid":false,"given":"Yoshiki","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8662-9421","authenticated-orcid":false,"given":"Nobuhisa","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4546-9606","authenticated-orcid":false,"given":"Kaoru","family":"Niimi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0493-1825","authenticated-orcid":false,"given":"Hiroaki","family":"Kajiyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/ctrv.1999.0119"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.26354"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-011-0203-y"},{"issue":"2156","key":"e_1_2_7_5_1","first-page":"1","article-title":"Brain metastases from ovarian cancer: current evidence in diagnosis, treatment, and prognosis","volume":"12","author":"Diagnosis E","year":"2020","journal-title":"Cancers (Basel)"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2019.03.004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","unstructured":"Wasserstrom WR Glass JP Posner JB.Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients [Internet]. 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