{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:04:50Z","timestamp":1789578290214,"version":"build-2803163510"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To explore left ventricular structural\/functional abnormalities in preeclampsia patients by using multimodal echocardiography and to analyze the cardiac impact in preeclampsia subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 103 individuals, including 64 preeclampsia patients and 39 healthy pregnant women were recruited for this study from 2019 to 2021. There were 34 patients with preeclampsia with severe features (SPE) patients and 30 with preeclampsia with nonsevere features (NSPE), including 9 with early\u2010onset NSPE (EO\u2010NSPE) patients, 27 early\u2010onset SPE (EO\u2010SPE) patients, 21 later\u2010onset NSPE (LO\u2010NSPE), and 7 with later\u2010onset SPE (LO\u2010SPE). All patients underwent multimodal echocardiography before treatment, including two\u2010dimensional, Doppler, and speckle\u2010tracking echocardiography, to evaluate left ventricular structure\/function. Analysis of variance was used to determine statistical significance across groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>EO\u2010SPE patients showed decreased left ventricular ejection fractions, peak longitudinal systolic strain at apical four\u2010chambers, peak circumferential, and radial systolic strain at the apical and mitral annular plane systolic excursion (MAPSE), and increased mitral regurgitation compared to other preeclampsia patients. Compared to LO\u2010NSPE and EO\u2010SPE patients, LO\u2010SPE patients showed increased left ventricular mass indexed to height<jats:sup>2.7<\/jats:sup> and early diastolic left ventricular diastolic filling\/mitral annular velocity, and decreased MAPSE and early\/late diastolic mitral annular velocity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EO\u2010SPE patients were characterized by left ventricular injury and systolic function reduced. LO\u2010SPE patients were characterized by left ventricular hypertrophy and reduced diastolic function. Multimodal echocardiography can detect myocardial injury in PE patients at an early stage.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15699","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T09:00:21Z","timestamp":1685610021000},"page":"2031-2039","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Assessment of left ventricular structure and function in preeclampsia subtypes by multimodal echocardiography"],"prefix":"10.1111","volume":"49","author":[{"given":"Lan","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Medical Imaging Center The First Affiliated Hospital of Jinan University  Guangzhou People's Republic of China"},{"name":"Department of Medical Ultrasound The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou People's Republic of 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