{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T17:07:15Z","timestamp":1774026435227,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.pericles-gcp.literatumonline.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>In anticipation of the future development of assisted reproductive technology (ART) and to smoothly introduce new technology, it is necessary to understand the current staffing status of the medical system and the current state of treatment, as well as the status of in vitro fertilization add\u2010ons, where the need for insurance coverage is currently a matter of debate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>ART facilities in Japan were surveyed (437 valid responses, response rate: 71%). Current staffing status of the medical system, implementation rates of ART, add\u2010on treatments, and medical supplies were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Despite the abundance of embryologists, nurses, and obstetricians and gynecologists in facilities, the majority of facilities lacked counselors, anesthesiologists, and other essential medical professionals. Conventional ovarian stimulation was widely adopted (median 120 [interquartile range 60\u2013300] cycles), followed by mild ovarian simulation (60 [30\u2013200]). Additionally, freeze\u2013thaw embryo transfer cycles (300 [120\u2013750]) were performed more frequently than fresh embryo transfer cycles (30 [30\u201360]). Among the add\u2010ons, assisted hatching (85.1%), chronic endometritis examination (77.2%) and treatment (76.9%), artificial oocyte activation (67.3%), endometrial receptivity analysis (64.2%), and endometrial microbiome analysis (58.9%) were relatively widely employed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The implementation of frozen\u2013thawed embryo transfer cycles, freeze\u2010all strategies, and add\u2010on treatments have become popular and widely accepted despite the lack of robust evidence regarding their safety and efficacy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15780","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T07:40:00Z","timestamp":1693208400000},"page":"2593-2601","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Fact\u2010finding survey on assisted reproductive technology in Japan"],"prefix":"10.1111","volume":"49","author":[{"given":"Sayaka","family":"Harada","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7560-316X","authenticated-orcid":false,"given":"Mitsutoshi","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5300-0037","authenticated-orcid":false,"given":"Hiromitsu","family":"Shirasawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Akita University Graduate School of Medicine  Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8815-5714","authenticated-orcid":false,"given":"Seung Chik","family":"Jwa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saitama Medical University  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2759-9159","authenticated-orcid":false,"given":"Keiji","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine and Endoscopy Sugiyama Clinic Marunouchi  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1071-5600","authenticated-orcid":false,"given":"Miyuki","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6660-1066","authenticated-orcid":false,"given":"Yutaka","family":"Osuga","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,28]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Director\u2010general for statistics, information policy and industrial relations","author":"Outline of Health, Labour and Welfare Statistics","year":"2021"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2020-106745"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12494"},{"key":"e_1_2_9_5_1","volume-title":"Assisted Reproductive Technology (ART) Report National ART Success 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ReproductiveFacts.org 2020. American Society for Reproductive Medicine."},{"key":"e_1_2_9_19_1","unstructured":"Research report on financial support for infertility treatment in foreign countrie. Nomura Research Institute Ltd."},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.05.015"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2019.04.005"},{"key":"e_1_2_9_22_1","unstructured":"Medical Service Fertility Treatment. Korea Health Industry Developmental Institute."},{"key":"e_1_2_9_23_1","unstructured":"Specific Treatment Support Project for Those Suffering from Infertility. Ministry of Health Labour and Welfare."},{"key":"e_1_2_9_24_1","unstructured":"National Patient Survey report. 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