{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T21:02:16Z","timestamp":1772571736401,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T00:00:00Z","timestamp":1693612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the long\u2010term survival outcomes of laparoscopic radical hysterectomy (LRH) and open radical hysterectomy (ORH) in International Federation of Gynecology and Obstetrics (FIGO) 2018 early\u2010stage cervical adenocarcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Based on the clinical diagnosis and treatment for cervical cancer in mainland China (Four C) database, the medical records of 1098 patients with FIGO 2018 early\u2010stage cervical adenocarcinoma were retrospectively reviewed. Long\u2010term and short\u2010term survival outcomes of the two groups were compared using a multivariate Cox regression model and the log\u2010rank method in the whole study population and after propensity score matching.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no difference in disease\u2010free survival (hazard ratio [HR] 0.921, 95% confidence interval [CI]: 0.532\u20131.595, <jats:italic>p<\/jats:italic>\u2009=\u20090.770) and overall survival (HR 1.168, 95% CI: 0.526\u20132.592, <jats:italic>p<\/jats:italic>\u2009=\u20090.702) between LRH (<jats:italic>n<\/jats:italic>\u2009=\u2009468) and ORH (<jats:italic>n<\/jats:italic>\u2009=\u2009468) in the risk\u2010adjusted analysis. LRH resulted in significantly lower estimated blood loss (342.7 vs. 157.5\u2009mL, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and shorter postoperative anal exhaust time (2.8 vs. 2.5\u2009days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) in risk\u2010adjusted analysis. The overall rates of intraoperative complications (2.4% vs. 4.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.100) and postoperative complications (7.5% vs. 6.2%, <jats:italic>p<\/jats:italic>\u2009=\u20090.437) showed no significant difference between the two groups. However, the LRH group had a significantly higher incidence of ureter injury (0.4% vs. 2.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.012) and great vessel injury (0.0% vs. 0.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.045) compared to the other group. No statistical variation in the site of recurrence was observed between the two groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.613).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LRH has comparable survival outcomes with ORH and was associated with earlier recovery in FIGO 2018 early\u2010stage adenocarcinoma of the uterine cervix. However, the LRH group had higher risk of ureter injury and great vessel injury.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15785","type":"journal-article","created":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T10:29:51Z","timestamp":1693650591000},"page":"2849-2859","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Laparoscopic versus open radical hysterectomy in <scp>FIGO<\/scp> 2018 early\u2010stage cervical adenocarcinoma: Long\u2010term survival outcomes after propensity score matching"],"prefix":"10.1111","volume":"49","author":[{"given":"Zhaohong","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Nanfang Hospital, Southern Medical University  Guangzhou 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