{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:36:32Z","timestamp":1747186592948,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To validate the diagnostic performance of Ovarian\u2010Adnexal Reporting and Data System (O\u2010RADS) ultrasound for preoperative adnexal lesions in an external center. The secondary aim was to evaluate the performance of a strategy test including O\u2010RADS ultrasound evaluation and subjective assessment of higher malignant risk lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred thirty patients with 158 ovarian\u2010adnexal lesions were enrolled in the study. Each lesion was assigned an O\u2010RADS score after real\u2010time ultrasound examination by one experienced radiologist. A second subjective assessment by an expert was performed for O\u2010RADS 4 and O\u2010RADS 5 lesions. The histopathological diagnosis was used as the reference standard.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 126 benign and 32 malignant adnexal masses were included in the study. The area under the receiver operating characteristic curve of O\u2010RADS ultrasound was 0.950, with a cutoff value &gt; O\u2010RADS 3. The sensitivity, specificity, and negative and positive predictive values were 100% (95% confidence interval [CI], 0.867\u20131), 83.3% (95% CI, 0.754\u20130.892), 60.4% (95% CI, 0.460\u20130.732), and 100% (95% CI, 0.956\u20131), respectively. For the strategy test, the sensitivity, specificity, negative and positive predictive values were 100% (95% CI, 0.867\u20131), 92.1% (95% CI, 0.855\u20130.959), 76.2% (95% CI, 0.602\u20130.874), and 100% (95% CI, 0.960\u20131), respectively. In comparison with O\u2010RADS ultrasound, the specificity and negative predictive value of the strategy test were slightly higher (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Good diagnostic performance of the O\u2010RADS ultrasound in adnexal lesions can be achieved by experienced radiologists in clinical practice. A second subjective assessment of sonographic findings can be applied to O\u2010RADS 4 and 5 lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.15831","type":"journal-article","created":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T12:01:43Z","timestamp":1700654503000},"page":"225-232","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of American College of Radiology <scp>Ovarian\u2010Adnexal<\/scp> Reporting and Data System ultrasound to predict malignancy risk in adnexal lesions"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0637-2679","authenticated-orcid":false,"given":"Ya","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ultrasound The Second Hospital, Cheeloo College of Medicine, Shandong University  Jinan Shandong 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Ultrasound The Second Hospital, Cheeloo College of Medicine, Shandong University  Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunchun","family":"Shao","sequence":"additional","affiliation":[{"name":"Center of Evidence\u2010Based Medicine, Institute of Medicine Science, The Second Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong 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