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A mapping biopsy in a large area from the vaginal wall to the vulva revealed that synaptophysin\/Ki\u201067\u2010positive tumor cells were scattered within the epithelium in multiple areas, suggesting a wide Pag\u2010S of NEC. Because tumor cells were found beyond the vaginal wall, the anterior pelvic exenteration was performed. Since we could pathologically confirm the complete resection and no distant metastases were detected, no adjuvant therapy was performed. Four years have passed since the initial treatment without any tumor recurrence. It is known that the prognosis of NEC of the cervix that invades beyond the cervix is poor; however, if there is a Pag\u2010S pattern, a radical surgical treatment can be considered.<\/jats:p>","DOI":"10.1111\/jog.15895","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T06:44:08Z","timestamp":1706769848000},"page":"758-763","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Neuroendocrine carcinoma of the uterine cervix with extensive pagetoid spread pattern"],"prefix":"10.1111","volume":"50","author":[{"given":"Azusa","family":"Sakurai","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Graduate School of Medicine Kyoto University  Kyoto City Kyoto 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