{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T06:50:16Z","timestamp":1773211816223,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pregnancy\u2010associated atypical hemolytic uremic syndrome (P\u2010aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P\u2010aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment.<\/jats:p>","DOI":"10.1111\/jog.15958","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T03:10:13Z","timestamp":1715224213000},"page":"1268-1272","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pregnancy\u2010associated atypical hemolytic uremic syndrome. Case report"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2493-2972","authenticated-orcid":false,"given":"Christopher","family":"Barrera\u2010Hoffmann","sequence":"first","affiliation":[{"name":"Servicio de Medicina Cr\u00edtica Hospital General Regional No. 1 \u201cLic Ignacio Garc\u00eda T\u00e9llez\u201d  M\u00e9rida Yucat\u00e1n Mexico"},{"name":"Facultad de Medicina Universidad Aut\u00f3noma de Yucat\u00e1n  M\u00e9rida Yucat\u00e1n Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yadira","family":"Mariaca\u2010Ort\u00edz","sequence":"additional","affiliation":[{"name":"Servicio de Medicina Interna Hospital General de M\u00e9xico \u201cDr. Eduardo Liceaga\u201d  Ciudad de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josu\u00e9 Giovani","family":"Ruiz\u2010Villa","sequence":"additional","affiliation":[{"name":"Servicio de Medicina Cr\u00edtica Obst\u00e9trica Hospital General de M\u00e9xico \u201cDr. Eduardo Liceaga\u201d  Ciudad de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lesllie Eugenia","family":"Cuevas\u2010Cruz","sequence":"additional","affiliation":[{"name":"Servicio de Medicina Hospital General de Cuernavaca \u201cDr Jos\u00e9 G. Parres\u201d  Cuernavaca Morelos Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda del Rosario","family":"L\u00f3pez\u2010Mendoza","sequence":"additional","affiliation":[{"name":"Servicio de Ginecolog\u00eda y Obstetricia Hospital General de M\u00e9xico \u201cDr. Eduardo Liceaga\u201d  Ciudad de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas Carlos","family":"Briones\u2010Gardu\u00f1o","sequence":"additional","affiliation":[{"name":"Servicio de Ginecolog\u00eda y Obstetricia Hospital General de M\u00e9xico \u201cDr. Eduardo Liceaga\u201d  Ciudad de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2019.11.004"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2018.02.007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00280117"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26854"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2018.08.002"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12763"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00620117"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2017.06.022"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2019.388"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2590"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016090995"},{"key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.circir.2016.02.001","article-title":"S\u00edndrome ur\u00e9mico hemol\u00edtico at\u00edpico en el embarazo","volume":"84","author":"P\u00e9rez Calatayud \u00c1A","year":"2016","journal-title":"Cirug\u00eda y Cir"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00376.2017"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-020-02100-4"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.15958","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jog.15958","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.15958","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T09:03:57Z","timestamp":1773133437000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.15958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,9]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/jog.15958"],"URL":"https:\/\/doi.org\/10.1111\/jog.15958","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,9]]},"assertion":[{"value":"2023-10-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}