{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:36:57Z","timestamp":1747186617218,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Angiotensin II receptor blockers (ARBs) are contraindicated during pregnancy because of fetal toxicity. All previous reports on adverse fetal outcomes involved women who continued to take low\u2010dose ARBs for hypertension and were unaware of the adverse effects. Herein, we report the case of a 23\u2010year\u2010old pregnant woman in her third trimester who experienced an ARB overdose after an argument with her partner. Pregnancy was complicated by transient oligohydramnios, and fetal magnetic resonance imaging suggested renal failure. Despite these concerns, the newborn had no morphological abnormalities or abnormal neurological findings. Renal impairment improved over time, and the infant grew well. A single overdose of ARBs in the third trimester can lead to fetal renal failure, similar to long\u2010term low\u2010dose ARB administration; however, favorable outcomes are possible. An overdose of ARBs may transiently cause renal failure, which may improve. The study findings may inform counseling for women who are unexpectedly exposed to an overdose of ARBs.<\/jats:p>","DOI":"10.1111\/jog.16003","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T03:55:03Z","timestamp":1718942103000},"page":"1425-1428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Overdose of angiotensin <scp>II<\/scp> receptor blocker in the third trimester of pregnancy: A case report"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-927X","authenticated-orcid":false,"given":"Ken","family":"Takahashi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Morikawa","sequence":"additional","affiliation":[{"name":"Department of Radiology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miku","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Pathology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7249-1537","authenticated-orcid":false,"given":"Osamu","family":"Samura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5079-0464","authenticated-orcid":false,"given":"Aikou","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,20]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1016\/j.jpeds.2015.05.045"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1002\/bdra.20102"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1038\/hr.2015.12"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1016\/0002-9378(80)90606-7"},{"key":"e_1_2_9_6_1","article-title":"Increased renal echogenicity in a preterm neonate kidneys with tubular dysplasia due to exposure to candesartan during pregnancy","volume":"20","author":"Bald M","year":"2005","journal-title":"Pediatr Nephrol"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.2174\/092986712803306411"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1097\/00004872-200018020-00001"},{"doi-asserted-by":"publisher","key":"e_1_2_9_9_1","DOI":"10.1136\/bmj.d5931"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1111\/j.1365-2125.2012.04388.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_11_1","DOI":"10.1002\/prp2.644"},{"doi-asserted-by":"publisher","key":"e_1_2_9_12_1","DOI":"10.1056\/NEJMoa055202"},{"doi-asserted-by":"publisher","key":"e_1_2_9_13_1","DOI":"10.3390\/ijms22147555"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.16003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:02:57Z","timestamp":1722556977000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.16003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,20]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/jog.16003"],"URL":"https:\/\/doi.org\/10.1111\/jog.16003","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"type":"print","value":"1341-8076"},{"type":"electronic","value":"1447-0756"}],"subject":[],"published":{"date-parts":[[2024,6,20]]},"assertion":[{"value":"2024-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}