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Chemotherapy used to treat cervical cancer can be divided into four categories: (1) preceding chemotherapy (neoadjuvant chemotherapy) to augment the effects of radical therapy (surgery or radiation therapy), (2) chemotherapy administered concurrently with radiation therapy, and (3) adjuvant chemotherapy administered after radical therapy. In addition, (4) chemotherapy is used to prolong survival and alleviate symptoms in patients who cannot be radically cured. Recently, molecular targeted agents, angiogenesis inhibitors, and immune checkpoint inhibitors have been incorporated into existing chemotherapy regimens. This review summarizes these trends along with the history of chemotherapy for cervical cancer.<\/jats:p>","DOI":"10.1111\/jog.16028","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T05:39:30Z","timestamp":1730266770000},"page":"79-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Latest findings in chemotherapy"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4223-1291","authenticated-orcid":false,"given":"Tohru","family":"Morisada","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine, Kyorin University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"National Cancer Center","author":"Cancer Information Service","year":"2022"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2019.0001"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1997.15.1.165"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.04.170"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.10.021"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.21.8909"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.58.4391"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(03)00425-8"},{"issue":"2","key":"e_1_2_11_10_1","article-title":"Neoadjuvant chemotherapy for locally advanced cervix cancer","volume":"2004","author":"Neoadjuvant Chemotherapy for Cervical Cancer Meta\u2010Analysis Collaboration (NACCCMA) Collaboration","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.9663"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(23)00147-X"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.04.007"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.179"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2024.35.e15"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.8.1606"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2020-002344"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31607-0"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2020.07.026"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.02105"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2112435"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2112187"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-000880"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-001135"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(21)00056-5"},{"issue":"1","key":"e_1_2_11_26_1","first-page":"47","article-title":"Efficacy and safety of trastuzumab Deruxtecan in patients with HER2\u2010expressing solid tumors: primary results from the DESTINY\u2010PanTumor02 phase II trial","volume":"42","author":"Meric\u2010Bernstam F","year":"2024","journal-title":"Clin Oncol"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.16028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T05:40:33Z","timestamp":1730266833000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.16028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":25,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/jog.16028"],"URL":"https:\/\/doi.org\/10.1111\/jog.16028","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-06-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}