{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T13:27:14Z","timestamp":1785245234467,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>In Japan, noninvasive prenatal testing (NIPT) has been performed by facilities accredited by the Japanese Society of Obstetrics and Gynecology since 2013. However, since 2016, with the implementation of NIPT, which can only be performed by blood sampling, non\u2010obstetricians have been involved in prenatal testing. Therefore, in July 2022, a new government\u2010involved NIPT certification system based on Health Sciences Council guidelines was introduced to ensure access to prenatal testing information for pregnant women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This survey was conducted in February 2023 and was the first survey after the certification system implementation. We conducted a web\u2010based survey of 1227 pregnant women and nursing mothers who underwent NIPT after July 2022 to evaluate their experiences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Respondents were categorized by certification status as certified (C: 56%), non\u2010certified (non\u2010C: 23%), or uncertain (Q: 20%). The C group with a higher mean age at examination (35.0\u2009\u00b1\u20094.5\u2009years) paid lower examination fees, received longer pre\u2010 and post\u2010examination explanations, and underwent more weekday examinations (80%) than the other groups. Most respondents, 67%, 48%, and 53% in the C, non\u2010C, and Q groups, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), stated that \u201cNIPT needs to be regulated by the government or academic societies.\u201d The non\u2010C group was more likely to say, \u201cInsufficient post\u2010test explanations at the laboratory made me more anxious,\u201d than the other groups when the testing results were non\u2010negative (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.015).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite government regulation, some pregnant women choose convenience over certified facilities, risking inadequate care. The government should ensure that NIPT is a safe option for all pregnant women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.16052","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T01:15:03Z","timestamp":1723684503000},"page":"1542-1551","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Impact of the new government\u2010involved noninvasive prenatal testing certification system on the awareness of pregnant women about noninvasive prenatal testing in Japan"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1150-4215","authenticated-orcid":false,"given":"Nahoko","family":"Shirato","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Sekizawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Miyagami","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miwa","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Yamada","sequence":"additional","affiliation":[{"name":"Division of Clinical Genetics Hokkaido University Hospital  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuko","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"},{"name":"Showa University Graduate School of Health Sciences  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Ikebukuro","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akane","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Showa University School of Medicine  Tokyo 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9003-1289","authenticated-orcid":false,"given":"Nobuhiro","family":"Suzumori","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yoshihashi","sequence":"additional","affiliation":[{"name":"Department of Clinical Genetics Tokyo Metropolitan Children's Medical Center  Fuchu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7249-1537","authenticated-orcid":false,"given":"Osamu","family":"Samura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University  Minato Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Sawai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hyogo Medical University  Nishinomiya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9387-1849","authenticated-orcid":false,"given":"Haruhiko","family":"Sago","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics National Center for Child Health and Development  Setagaya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torayuki","family":"Okuyama","sequence":"additional","affiliation":[{"name":"Department of Clinical Genomics Saitama Medical University  Saitama 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