{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:35:54Z","timestamp":1790631354594,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe an exceptionally rare case of epithelioid trophoblastic tumor (ETT) in a patient with recurrent implantation failure (RIF). A 38\u2010year\u2010old Japanese woman, gravida 1, para 1, was diagnosed with RIF following three unsuccessful cryopreserved morphologically good embryo transfers with hormone replacement cycles after thawing. She underwent hysteroscopy and endometrial biopsy to exclude chronic endometritis but was referred because ETT was strongly suspected. Following a preoperative diagnosis of stage I ETT, she underwent laparoscopic total hysterectomy and bilateral salpingo\u2010oophorectomy. A yellowish elevated lesion was observed in the lower uterine body. Immunohistochemical staining was negative for human chorionic gonadotropin and human placental lactogen and positive for p63, with a Ki\u201067 proliferation index of &gt;10%. She was diagnosed with stage I ETT, but postoperative chemotherapy was not administered because of the lesion location and occurrence within 48\u2009months of the prior term delivery. She had no recurrence at 24\u2009months postoperatively.<\/jats:p>","DOI":"10.1111\/jog.16259","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T04:35:54Z","timestamp":1741754154000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Epithelioid trophoblastic tumor diagnosed during a thorough examination of recurrent implantation failure: A case report"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1271-9082","authenticated-orcid":false,"given":"Yasuhiko","family":"Kamada","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Haraga","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoyuki","family":"Ida","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4031-8091","authenticated-orcid":false,"given":"Shoji","family":"Nagao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Yanai","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Masuyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama University Hospital  Okayama Japan"},{"name":"Department of Obstetrics and Gynecology Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Abu\u2010RustumNR CamposSM YasharCM BradleyK CamposSM ChonHS et al.Gestational trophoblastic neoplasia version 2.2024 NCCN Clinical Practice Guidelines in Oncology (NCCN 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