{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T16:41:55Z","timestamp":1782146515510,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T00:00:00Z","timestamp":1743897600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>To identify reliable indicators to predict the occurrence of metabolic syndrome (MetS) and to provide an effective way to prevent it in polycystic ovary syndrome (PCOS), we explored the relationships between triglyceride\u2010glucose index (Ty\u2010G), lipid accumulation product (LAP), lipid accumulation product ratio, and MetS.<\/jats:p><\/jats:sec>Methods<\/jats:title>We detected the relationship between the Ty\u2010G index, LAP, lipid ratio, and incidence of MetS. In addition, we classified the Ty\u2010G index and LAP into tertiles to determine the efficacy of these indicators in predicting the risk of MetS. Finally, the effects of the Ty\u2010G index, LAP, and lipid ratio on the prediction of MetS were evaluated with the receiver operating characteristic (ROC) curve.<\/jats:p><\/jats:sec>Results<\/jats:title>Our results indicate that the incidence of MetS was 38% in 134 patients with PCOS, and that the Ty\u2010G index, LAP, and lipid ratio were independent risk factors for MetS. In addition, the incidence of MetS significantly increased with Ty\u2010G index and LAP. The ROC curve showed that the Ty\u2010G index, LAP, and lipid ratio all showed good performance in predicting the occurrence of MetS in PCOS patients, but the Ty\u2010G index had the highest predictive value, with a cut\u2010off value of 8.70.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Our study revealed that the Ty\u2010G index plays an important role in predicting the occurrence of MetS in PCOS patients. In addition, monitoring blood glucose and lipid levels is an effective approach for preventing MetS in PCOS patients clinically regardless of age, and weight management should be strictly implemented in overweight and obese patients to prevent MetS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.16283","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:20:42Z","timestamp":1743985242000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The predictive value of triglyceride\u2010glucose index, lipid accumulation product and lipid ratio on metabolic syndrome in polycystic ovary syndrome patients"],"prefix":"10.1111","volume":"51","author":[{"given":"Ning","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Yan'an University Affiliated Hospital Yan'an Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8251-5194","authenticated-orcid":false,"given":"Xiao\u2010Ning","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Yan'an People's Hospital Yan'an Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Pathophysiology, Yan'an University Yan'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep399"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.120677"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-018-0812-z"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejendo\/lvad077"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.001180"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12762"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2261-5-26"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1279978"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-90648-y"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.15605\/jafes.034.01.04"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0288"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-024-02412-6"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S387942"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.03.085"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2023.07.025"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15143168"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2018.24"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.57"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2019.01.002"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000167408.30893.6b"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2023.2172154"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.12.027"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.3.309"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.773781"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.4103\/jhrs.jhrs_114_21"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4755-12-7"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2015.1117069"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2024.04.130"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-020-01054-z"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-021-01268-9"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-022-01546-0"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2019-0310"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13133941"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-022-01114-z"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.16283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:52:56Z","timestamp":1745470376000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.16283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/jog.16283"],"URL":"https:\/\/doi.org\/10.1111\/jog.16283","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e16283"}}